tag:blogger.com,1999:blog-44472491235196583472024-03-16T08:08:59.659+01:00SuppVersity - Nutrition and Exercise Science for EveryoneWhere BRO- and PRO-Science Unite in the Spirit of True WisdomAdel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comBlogger23125tag:blogger.com,1999:blog-4447249123519658347.post-69707702199384979472018-10-15T03:35:00.000+02:002018-10-15T03:41:57.364+02:00If the Androgen Receptor Response to Training Determines Your Gainz, the Question is: How Can You Optimize 'ur AR Density? Training-, Diet-, and Supplement-Effects Reviewed
Your androgen receptor status may not just determine how much muscle you gain - the data from Morton et al. seems to suggest that it even determines if you make visible muscle gains, at all.
Unless you've missed following the SuppVersity on Facebook, yet, you will remember my recent, highly popular post which previewed the results of a recent study from the McMaster University in Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-66355007629199386392015-12-30T09:18:00.000+01:002015-12-30T16:19:18.044+01:00Ecdysterone Beats Popular Anabolics!? Plus 75% Muscle Size in 21 Days in Rats - More Than DHT, IGF-1, Dianabol...
Parr et al. suggest that ecdysterone should be added to the WADA list.
Actually, I didn't plan to write a SuppVersity article about an agent of which everybody says that it's a waste of money, but I have to admit that the conclusion that "ecdysterone exhibited a strong hypertrophic effect on the fiber size of rat soleus muscle that was found even stronger compared to the test compounds Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-37835535860278624502015-12-25T07:44:00.000+01:002015-12-25T10:42:33.952+01:00Hormonal Response to Exercise, Revisited: A Consequence, not a Determinant of Your Mood, Effort & Performance
Studies in men suggest no effect of the hormonal response on training outcome - What about women? A news study provides insights that may be relevant for both female and male gymrats.
It has been a few years that I last wrote about the "hormonal ghost". Back in the day, Stuart M. Phillips published an excellent paper that debunked the myth of a mechanistic link of post-exercise increases in Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-14856871956735887172014-01-01T15:36:00.005+01:002014-01-01T15:37:46.639+01:00Low Testosterone, Low Life Expectancy: Plus: Chinese vs. US - Do the Same Reference Ranges Apply for Everyone?
This is what Photoshop and creativity can tell us about aging men.
It has been a while since we've taken a closer look at the effects of testosterone deficiency and its replacement aka TRT. Basically that's why I decided not to waste the interesting findings from a recently published study in the The Journal of Clinical Endocrinology and Metabolism (Yeap. 2013) in the Facebook News. In Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-24180318769474009452013-11-26T18:25:00.001+01:002013-11-27T05:23:26.241+01:00High Intensity Training + Mesterolone Yield Muscle- and Fiber-Type Specific Size Gains Of Up To 100% & More
Want to learn more about fiber types? ➫ review past SuppVersity articles
I am not telling you a secret, when I say that testosterone alone - in the absence of training - will lead to significant increases in skeletal muscle mass (if you think that sounds like a secret you must have missed my previous article from the "Intermittent Thoughts on Building Muscle" series | read more). To a certainAdel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-25089027313550912762013-11-16T15:04:00.004+01:002015-08-28T05:42:44.876+02:00TReaTing Diabesity With Testosterone!? If You Keep DHT in Check + Stay Away From Aromatase Inhibitors, It May Work
It probably won't turn an overweight pre-diabetic into a fitness model, but a getting a TRT script has the potential of changing a man's physical and psychological health for the better.
Despite the fact that more and more men recognize the benefits of supervised testosterone replacement therapy (TRT) and the bodybuilding and fitness community cherishes 'their BIG T' as the be-all-and-end-all,Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-39805664558535129232013-10-15T15:55:00.001+02:002014-07-17T08:27:42.092+02:00Creatine, DHT, Hair Loss & Prostate Cancer - Bro-Scientific Old Wives' Tales or Possible Side Effect? Plus: (Non-)Sense Creatine Loading, Exercise Induced 5-α Reduction & More
Poor guy! Must have taken too much creatine and treated his hair for muscle ;-) Ok, seriously, creatine may have helped a little that he was able to build this impressive physique, but the hair? Come on, seriously!?
If you have been around the bulletin boards of the fitness and bodybuilding community, I am pretty sure you will have heard about creatine induced increases in dehydrotestosterone Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-35524242759686975242013-06-06T16:33:00.000+02:002013-06-06T17:04:22.092+02:00Serum & Intramuscular Testosterone, DHT and Androgen Receptor Response to High vs. Low Volume Training
Another set for another ng of testosterone? Does it work that way and is it worth it - not just on paper, but in terms of real gains?
I know that we don't know! And among the many things we don't know the influence of the post-workout elevation in the long-thought "anabolic" hormones testosterone, growth hormone, and co. is unquestionably one of my personal favorites. You've read about it, Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-40983390955983225092013-05-11T15:44:00.001+02:002020-01-07T04:43:53.030+01:00Androgen 3-Some: BPA Exposure & Free Testosterone in Men. TRT Good For the Prostate. DHT, Alopecia (Hair Loss) & Monascus Fermentation. Plus: Mycotoxins in GCB Supps
Coffee and green coffee bean extracts are by no means the only way by which you are exposed to mycotoxins. Corn, for example, is likewise a favorite for the toxic mold. The same goes for almost all other grains. Common routes of exposure are, amongst others cereals, breads, wines, and even mils and meats (of swine ad turkey, not chicken; Duarte. 2010)
36%, 32%, 10%, and 16% these are the Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-68859153697033454052013-01-14T17:48:00.001+01:002013-01-14T17:48:26.013+01:00Exercise Research Quickie: HIIT vs. Steady State, More on the Hormonal Response. Light Training, High TUTs & Peak Contractions - Not Just for The Elderly. Train Your Left, Grow Your Right Leg - Contralateral Training Effects
The role of the innervations between our muscles as well as to our brain is often overlooked, when we are talking about size gains. The image shows stained nerve fascicles from the Song study, which brings this wiring back onto the radar.
I know that we have had the short news on Saturday only and that there are of course tons of short news on Facebook everyday, but the studies I am going to Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-1352484611079856882012-07-28T17:50:00.001+02:002012-08-16T16:40:38.806+02:00On Short Notice: Insanity vs. TurboFire - What's the Best HIIT Regimen? Plus: USA vs. China, Chews vs. Raisins, Epi-Sesamine vs. Body Fat, Exercise vs. Neurotoxins & More
Figure 1: The latest medal prognosis for Olympia 2012 by researchers at the Department of Economics at the Ruhr-Universität Bochum in Germany (Otten. 2012) - I must admit I am curious how accurate this prognosis will be... what's your take? The US or China? Who's going to take the lead?
The Queen has officially opened the Olympic Games 2012 and the games have their first doping case - those ofAdel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-10857756607084811682012-06-01T17:44:00.002+02:002012-06-02T12:32:54.336+02:00Less Than 15mg of DHEA Exert Identical Beneficial Effects on Insulin Sensitivity as 1h of Cardio 5x Per Week. Both Effects Mediated Via Increases in Intra-Muscular DHT
Image 1: It has long been established that diabetics have particularly low DHEA levels (Loviselli. 1994), but what's the chicken and what's the egg here?
It is quite funny, sometimes you don't hear about certain supplements, (pro-)hormones, exercise-modalities etc. in years and then, all of a sudden, there are two studies on the respective topic in one week; and moreover, two pretty Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-36989134019754098182012-05-18T17:18:00.000+02:002012-05-19T09:03:02.692+02:00Chest Fat, Bitch Tits, Chesticles, Gynecomastia, Lipomastia and Co.: Infinite Ways to Name it, Only 5 to Get Rid of It
Image 1: Is it what he eats, is it what he drinks or is it just andropause? Whatever it may be, Jack does not have the "classic gyno".
In the last installment of this two-part series on gynecomastia, lipomastia and co. we have seen that the number of appellations this common, mostly benign enlargement of the male breast has been given, is easily outnumbered by the potential, mostly Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-19462255100882152342012-03-12T18:19:00.001+01:002015-10-16T09:56:34.573+02:00Dustasteride Doesn't Hamper Mass & Strength Gains on TRT, but Compromises the Fat Loss Effects of Testosterone and Does Not Reduce Any of the Side Effects
Image 1: I guess after the publication of his latest study, Mr. Bhasin will have a bad standing with the pharma reps from GlaxoSmithKline & Co ;-)
What happens if you take a couple of healthy guys and put them on a cycle... ah, pardon, I mean, "put them on hormone replacement therapy"? Assuming that you have paid attention in the seminars of the Intermittent Thoughts Series on Building Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-76104211954780661892012-01-29T17:17:00.000+01:002017-06-29T02:26:33.679+02:00Intermittent Thoughts on Building Muscle: A Preliminary Conclusion - Exercise, mTOR/AKT/MAPK, IGF-1, Testosterone, Estrogen, DHT, Nutrition, Supps & Sleep
Image 1: Arnold obviously is flabbergast that neither of the factors mentioned in the title of this blogpost was necessary to build the impressive physique of the Arnold statue which now stands in front of the Schwarzenegger Museum.
I don't know if some of you have seen it, but on January 3, 2012, ScienceDaily published a brief news-item titled "How work tells muscles to grow". It relates to aAdel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-89401747423485978882012-01-22T18:28:00.000+01:002013-11-26T05:56:59.912+01:00Intermittent Thoughts: Dihydrotestosterone (DHT) - Bigger, Stronger, Faster or just Balder, Fatter and Unhealthier?
Image 1: The ancient Greek ideal of the male body has probably more to do with DHT than the freaky physiques of today's IFBB Pro bodybuilders.
I guess after the revelations about the importance of estrogen in the process of skeletal muscle hypertrophy in the last installment of the Intermittent Thoughts you will probably be eager to hear what its male counterpart dihydrotestosterone (DHT), is Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-52280912558681610162012-01-13T17:40:00.002+01:002015-09-21T04:32:09.738+02:00Problems with High or Low DHT? Use Rice or Safflower to Inhibit and Sorghum to Promote 5-Alpha Reductase!
Image 1: High or too low DHT levels? Nature has the cure for both. Lower your DHT levels with rice bran or safflower flower extracts or raise it with a crude extract from Sorghum bicolor seeds.
Hairloss for men, and even more so for women, is certainly one of the nastiest side effects of either naturally or artificially induced hormonal disturbances. And while the vilification of DHT as the #1Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-53638428424206176812011-06-11T07:43:00.001+02:002011-06-11T07:45:16.809+02:00Andropause? Low Testosterone? At Risk of Developing Diabetes? Get a Free Hormonal Panel and Access Your Personal Health Risks With an Old-Fashioned Measuring Tape.
Image 1: Not as realiable as bloodwork,
but a valid first indicator of testosterone
levels and metabolic health in general
(image from Millionlineincome)
I have been writing about getting hormones tested before. And if you listened to Thursday's episode of Super Human Radio and tuned in even before I was on, you will have heard Dr. Crisler from "All Things Male" talk about the Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-79986780751027873002010-12-15T03:40:00.002+01:002010-12-15T03:40:00.951+01:00Positive/Negative Effects of Normal/High DHT on Metabolic PathwaysRegular visitors of the SuppVersity will certainly remember some of my previous posts about the false demonization of DHT. A new study coming from the Institute of Endocrinology in Prague (Duskova. 2010) supports the view that "optimal" and not low DHT levels are what men should be striving for.
Theorizing that DHT as a non-aromatizable androgen could be responsible for a male type fat Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-44345367704319221342010-11-22T03:34:00.001+01:002010-11-22T03:34:00.576+01:00DHT Safer Than Previously Thought: High Blood DHT does not Induce Prostate CancerRegular visitors of the SuppVersity will know that the stigmatization of DHT goes without reasonable and conclusive scientific research. In their editorial to the Annals of Internal Medicine Swerloff & Wang (Swerloff. 2010) conclude from the results of more recent studies into the various effects of DHT on different tissues:
In normal men, serum DHT levels are approximately 10% of the serum Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-43535185586086419882010-11-01T03:36:00.000+01:002010-11-01T03:36:00.659+01:00Fenugreek Supplement Increases Upper- and Lower-Body Strength and Body compositionFenugreek is an ingredient in several recently released dietary supplements, most claim to increase testosterone, something a recent study (Poole. 2010) on the effect of supplementation with a commercially available 500mg fenugreek supplement does not substantiate.
Table 1: Within and between group hormonal changes from baseline (T1) through week 8 (T3)
If you have a look at table 1, you will Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-26811598488841030562010-07-19T07:12:00.001+02:002010-07-19T07:12:00.447+02:00Androsterone a Major Factor in Sexual DesireA 2006 study (Bloch. 2006) (re-)published in Arch Gen Psychiatry. 2006;63:450-456 had a closer look on the effect of neurosteroids on sexual function in men.
The results clearly indicate that androsterone (ADT, chemical structure on the left; source: HMDB: Androsterone), a potent neurosteroid, some "bros" misunderstand as a precursor or pro-hormone to testosterone and estrogen (actually Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.comtag:blogger.com,1999:blog-4447249123519658347.post-373166881552304542010-07-18T02:56:00.016+02:002010-07-18T18:17:50.251+02:00Is DHT Really the 'Bad and the Ugly'?Fellow men, common (bro-)science tells us that dihydrotestosterone (DHT, molecular structure see image on the right. HMDB) will make your hair fall out and trigger cancerous growth of your prostate. Current research, however, suggests that Estrogen might just as well be the real culprit when it comes to unwanted growth a few inches above your testes. This is, as Williams (2010) phrases it, part Adel Moussahttp://www.blogger.com/profile/11282066708304898697noreply@blogger.com