|Even on the five fasting days per month your plate doesn't have to be completely empty. Real foods, however, weren't served in this trial.|
Now, as effective and healthy as it may be, fasting is not exactly what the average pre-diabetic (of whom the study at hand shows that he would benefit most) wants to do and/or what he or she can adhere to in the long run.
To test whether it may not even be necessary to fast for weeks and months, Min Wei et al. conducted a randomized clinical trial with 100 generally healthy participants. With a cross-over after 50% of the study period of three months, the study ensured that all subjects were fed the fasting-mimicking diet (FMD) group for 3 months. Aside from being low in calories and protein -
- day 1: ~4600 kJ = 1100kcal | 11% protein, 46% fat, and 43% carbohydrate
- day 2-5: ~3000 kJ = 717kcal | 9% protein, 44% fat, and 47% carbohydrate
|Figure 1: Overview of the study design (left) and post hoc comparisons for changes in risk factors for age-related diseases and conditions by baseline subgroups (right | Wei 2017).|
|Figure 2: Overview of changes in several markers of metabolic and overall health (Wei 2017).|
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