|Photos like this helped BSN sell truckloads of their "mother of all pre-workouts" NO XPlode!|
What? None of them worked for you? Well luckily the next "big thing" is already looming on the horizon: "Oral adenosine-5’-triphosphate (ATP) supplements," of which you'd think that they would be used to deliver immediate energy, are probably soon going to be marketed as "pump supplements".
Why? Well, let me just cite the title of a recent study from the Auburn University, the University of Tempa, the University of Missouri-Columbia and the a couple of companies with a vested interest in preferably beneficial study outcomes:
"Oral adenosine-5'-triphosphate (ATP) administration increases blood flow following exercise in animals and humans" (Jäger. 2014)
What? You're not impressed? Me neither, even though the body surface area, species adjusted human equivalent doses (HED) of either 100 mg (n=4), 400 mg (n=4), 1,000 mg (n=5) or 1,600 mg (n=5) of oral ATP as a disodium salt (Peak ATP®, TSI, Missoula, MT) the rodents in the study at hand received, the fact that the 400mg dosage of ATP that was used in the human arm of the study (12 resistance-trained male participants; 400 mg of ATP as a disodium salt daily 30 minutes before breakfast for 12 weeks + 400 mg of ATP 30 minutes prior to an acute elbow flexor bout consisting of 3 sets of 20 contractions at 50% of the subject’s 1-RM) produced rather mediocre elevations of post-workout.
|Figue 1: Changes in Brachial Diameter at weeks 1, 4, 8, 12 were compared to control week by a paired t-test, ‡|
p < 0.01, *p < 0.05 and +p < 0.10 (Jäger. 2014)
If it were not for the previously reported increases muscle mass, size and performance gains in Wilson et al.'s complex 12-week study with previously strength-trained subjects, I would yet say that we are probably dealing with yet another imposter supplement (re-read previous article).
- Jäger, R. et al. "Oral adenosine-5'-triphosphate (ATP) administration increases blood flow
following exercise in animals and humans." Journal of the International Society of Sports Nutrition. 2014:11-28
- Wilson JM, Joy JM, Lowery RP, Roberts MD, Lockwood CM, Manninen AH, Fuller JC Jr, De Souza EO, Baier SM, Wilson SMC, Rathmacher JA. "Effects of oral adenosine-5'-triphosphate (ATP) supplementation on athletic performance, skeletal muscle hypertrophy and recovery in resistance-trained men." Nutr Metab (Lond). 2013:10:57.