|Is H+ rich water more effective than other 'snake oil versions' of water?|
As Raymond rightly points out, the use of H+ water "seems to be a big deal in longevity circles, and perhaps it holds promise for 'our crowd' as well". The obvious question is: rightly so? Or, more specifically, is there credible evidence that H+ water has ergogenic and health-promoting effects in gymrats, athletes, and Mr. & Mrs. Average Joe.
Unfortunately, the best evidence in favor or H+ therapy comes from rodents, where hydrogen gas of less than 4 % was given by inhalation. If we follow Ichihara, et al. and summarize the results of pertinent studies, we would find a broad range of pathologies that includes 31 disease categories and 166 disease models, including human diseases, as well as treatment-associated pathologies with a predominance of oxidative stress-mediated diseases and inflammatory diseases.
|Table 1: Overview of Clinical trials published as of June 2015 (from Ichihara, et al. 2015).|
In humans and with respect to the significantly more popular consumption of H+ water, however, we have almost only pilot studies like the one by Aoki et al. (2012):
- Anti-fatigue effects in soccer players (Aoki, et al. 2012) -- In the study from the University of Tsukuba, each of the 10 soccer players who participated in the study was examined twice in a crossover double-blind manner; they were given either HW or placebo water (PW) for one-week intervals. Subjects were requested to use a cycle ergometer at a 75 % maximal oxygen uptake (VO2) for 30 min, followed by measurement of peak torque and muscle activity throughout 100 repetitions of maximal isokinetic knee extension. Oxidative stress markers and creatine kinase in the peripheral blood were sequentially measured.
Don't confuse H+ water with deep sea water (DSW): If you want to learn more about the latter, I suggest you read the most recent review from Malaysia (Nani, et al. 2016) | download for freeWhether that's also why H+ has been found to inhibit the growth of colon cancer cells in vitro and if the results of Runtuwene, et al. have any real-world relevance, requires further research.
|Figure 2: Schematic summary of molecular mechanisms of hydrogen (Ichihara. 2015).|