Saccharin Affects Weight, Blood Lipids, Glucose & Liver Markers at Doses Equiv. to 3 Packs of Common Sweetener
|Implications for diet coke? None!|
But let's tackle one thing after another. In contrast to the myths about aspartame which are still totally unfounded, the rumors about ill effects of saccharin on kidney and liver metabolism have been concrete enough for all the major players to pull saccharin from their products (see Table 1).
In fact, Tab, a diet cola soft drink introduced in 1963 and was created by Coca-Cola after the successful sales and marketing of Diet Rite cola, owned by The Royal Crown Company has long disappeared from the market... for a reason?
|Table 1: Overview of the amounts of artificial sweeteners in the most popular sodas (Wikipedia. 2015)|
|Figure 1: Changes in markers of liver and kidney health (left) and antioxidant status (right), in the former all changes were statistically significant, for GSH & co only the changes in the high dose group were (Amin. 2015).|
There is more than one reason not to jump to potentially unwarranted conclusions
I will not go into detail on the dozens of spelling and grammar mistakes, as this is nothing that impairs the accuracy of the experimental results, but the fact that the researchers report the diet composition as follows,
"Rats were nourished on the regular basal diet and supplied with tap water and the contents of experimental diets were according to Kim et al., , it composed of: lipid 5%, carbohydrates 6%, protein 20.3%, fiber 5%, salts 3.7%, and vitamins 1%" (Amin. 2015),makes me scratch my head. It's afte all not only that the figures don't add up. If you follow up on the reference, you will find that Kim et al. (2005) used a low and a high fat diet of which none contained only 5% of lipids (instead it's 11.7% and 40%).
|Of these three only the violet packet still contains saccharin. Most other sugar-replacements and many sugar-reduced foods rely on other agents.|
|Figure 2: Changes in body weight gain, makers of lipid and glucose metbolism, only full bars are stat. sign. (Amin. 2015).|
- Amin, Kamal Adel, and Hessah Mohammed AlMuzafar. "Alterations in lipid profile, oxidative stress and hepatic function in rat fed with saccharin and methyl-salicylates." International Journal of Clinical and Experimental Medicine 8.4 (2015): 6133.
- Kim, Ji Hyun, et al. "Effect of crude saponin of Korean red ginseng on high-fat diet-induced obesity in the rat." Journal of pharmacological sciences 97.1 (2005): 124-131.
- Udem, Samuel Chukwuneke, and Emmanuel C. Nwobodo. "Investigation into the short-term effect of ingestion of different concentrations of saccharin sodium on some hematological and biochemical profile of rats." Comparative Clinical Pathology 20.5 (2011): 471-474.
- Wikipedia contributors. Tab (soft drink) [Internet]. Wikipedia, The Free Encyclopedia; 2015 Jul 4, 23:49 UTC [cited 2015 Jul 5]. Available from: https://en.wikipedia.org/w/index.php?title=Tab_(soft_drink)&oldid=669980732.