|Image 1: Does this remind you of |
someone at your local gym? (Image
from Stanford School of Medicine)
Published in the latest issue of the clinical and experimental branch of Metabolism Li Fu and his colleagues report the results of an experiment in the course of which 40 mice were assigned to one out of four intervention groups, two of which exercised on a mouse-treadmill for 60min/d five times per week in the course of the 6 week experiment:
- normal chow + treadmill exercise (NE)
- high fat diet + treadmill exercise (HE)
- normal chow + sedentary (NC)
- high fat diet + sedentary (HC)
|Figure 1: Changes in body weight and blood parameters vs. sedentary control on normal diet |
(calculated based on data from Fu. 2011)
|Figure 2: Univariate variance analysis on body weight and plasma parameters (data adapted from Fu. 2011)|
These results stand in line with observations of Gary O'Donovan and colleagues (O'Donovan. 2011), published in the same journal. In a cohort of 183 nonsmoking white men aged 35 to 53 year O'Donovan and other researchers from the United Kingdom found profound differences in traditional and novel cardiometabolic risk factors (high-density lipoprotein cholesterol, triglycerides, alanine aminotransferase, and insulin resistance) between subjects who were fat and fit (like the exercised HFD mice) and those who were fat and unfit (like the unexercised HFD mice).
|Image 2: Check out Johan's|
amazing transformation to see
what mind-boggling results
you can achieve.