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Eating 75-100g Fat (M-/PUFA) in the AM Improves Glucose (7-8%), Insulin (40-60%), Trigs (4-16%), GSH & MDA (40-75%)

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If we assume that the protein fried eggs with its comparatively low insulinogenicity is not a problem (unlike your whey, for example), avocado and eggs fried in olive oil is the perfect breakfast to replace the liquid test meal used in the study. There's no debating that increased amounts of free fatty acids in the blood will impair your insulin sensitivity, as they should be there only, when your supply of carbohydrate is running out, AMPK and with it the expression of lypolytic enzymes increase and the triglycerides from your fat stores are broken down into free fatty acids and released into your bloodstream where they can be used by liver, muscle and other organs as an alternative energy source. Now, the word "alternative" is of paramount importance, here, because you'll find yourself being in (diabetic) trouble if those FFAs pile up on top of high glucose levels. This is what happens with the SAD diet and its high carbohydrate and  fat content (and energy!) ...
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Six Cups Of Coffee (900mg/day): Three Too Much or Just About Right to Speed Up Lipolysis & Fatty Acid Oxidation?

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The human equivalent of almost 900mg caffeine per day used in the study at hand did some good, but it also did some harm - read more and decide for yourselves which one you'd consider more important. It amazes me time and again. Coffee and caffeine in particular are unquestionably the best-researched "supplements", nutraceuticals, drugs, or whatever you want to call. Yet, nevertheless, the number of interesting studies is increasing day by day. Let's see... 2.3+ studies related to caffeine in one way or another were published per day in 2012 and as of now it looks, as if we would easily top that this year. But enough of those stats. Let's get to one of the latest of the 515 hits for this year and take a look at what Eun-Young Choi and Yun-Ok Cho from the Department of Food and Nutrition at the  Duksung Women's University in Seoul has to bring to the table. What? Another rodent study? Yeah, I hear you. I would also prefer if the Korean scientists had...
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19x Increase in Growth Hormone 60min After Ingestion of 1g of Glycerophosphocholine (GPC) in Young Male Subjects

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Image 1: Don't worry one thing is sure - GPC won't give you a gut like that ;-) A couple of days ago, I have written about the exorbitant choline consumption of some of bodybuilding legends, Randy Roach writes about in his Muscle Smoke & Mirrors Vol. II   and to be honest, I was quite surprised that among the many responses I got, none broached the issue of the latest and greatest supplemental choline spin-off: Glycerophosphocholine, or short GPC - a supposedly superior, because fat-bound (hence "glycero" as in "glycerol) and highly bioavailable bean-derived form of choline. Whatever the reasons may be, I suppose you still won't mind to hear that a recent experiment that was conducted at the Faculty of Sport and Health Science of Ritsumeikan University in Shiga, Japan, yielded quite interesting results with respect to the endocrine and metabolic short-term effects of 1,000mg of GPC in 8 healthy male (25+/1y) subjects (Kawamura. 2012). 19x more gr...
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Fat & Fit! Cardio Training Triggers Genetic Switches Which Won't Make you Lean, But Maybe Healthier.

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Image 1: Does this remind you of someone at your local gym? (Image from Stanford School of Medicine ) As a trained physicist I am more interested in the "why's" than in the "what's". It is old hat that the combination of diet (usually incorporating a moderate caloric reduction) and exercise still is the most promising way to sustainable weight loss and metabolic health . The molecular and genetic underpinnings of their almost magical synergy, however, have still not been 100% elucidated. A recent study ( Fu. 2011 ) from the Tianjin Medical University in Tianjin, China, does now contribute another piece to the complex puzzle that is our metabolism. Published in the latest issue of the clinical and experimental branch of Metabolism Li Fu and his colleagues report the results of an experiment in the course of which 40 mice were assigned to one out of four intervention groups, two of which exercised on a mouse-treadmill for 60min/d five times p...
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