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Ask Dr. Andro: What Are Human Equivalent Doses (HED) and How Do I Calculate Them?

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Image 1: Rat & guinea pig. Both very popular animal models. Both about the same size and weight, but with very different reactions to identical treatments. I won't waste too many words on this being a new series on the SuppVersity , I suppose the name "Ask Dr. Andro" is self-explanatory. It is based on questions posted in the comment section that are relevant for the majority of the visitors and require and deserve a more sophisticated response. So, if you want your question answered, learn a lesson from "Learner" who posted the following question in the comment section of " Spicing Up Fat Loss: Structural Similarity to Melanocortin-4 Agonists Powers Piperine's (Black Pepper Extract) Fat Loss and Lipid Lowering Effects ". Question from "Learner" : Why is the mg/kg dosing ratio different for humans than rats, and does that vary by the agent? Answer from Dr. Andro : Most of what we know about the effects of (new) drugs, ...
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Bodybuilding for Pekin Ducks: L-Arginine Supplementation Gets Poultry Stage Ready. More Muscle, Less Fat.

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Image 1: Not your usual exercise and nutrition science magazine: The Journal of British Poultry Science ( Taylor Francis Group . 2011) Those of you who have followed the Amino Acids for Super Human Series on Carl Lenore's Super Human Radio will be familiar with the manifold benefits supplementation with the conditionally essential amino acid l-arginine has on blood pressure, glucose metabolism, endothelial health, etc. If you also listened to the last installment of the series ( Amino Acids for Super Humans III: The Sulfur Amino Acids ), you will know about my special affiliation with chicken, with chicken. Taken together, this may in parts explain, why today's SuppVersity newsitem is about a study from the Chinese Hubei Key Laboratory of Animal Nutrition and Feed Science in Wuhan ( Wu. 2011 ). In their study that has been published in the latest issue of the "famous" Journal of British Poultry Science (...
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