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NAFLD, Non-Alcoholic Fatty Liver Disease, the Gateway to Diabesity - Which Supplements Help? A Dozen Suggestions

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There's a whole arsenal of vitamins & herbals that's supposed to either protect you from or even cure NAFLD. NAFLD is emerging as one of the most common chronic liver diseases worldwide, and represents one of main cause of hepatology referral in some centers. NAFLD is a clinical syndrome that ranges from simple fatty liver, to non-alcoholic steatohepatitis, to advanced fibrosis, and cirrhosis. It's directly liked to diabesity by its ties to insulin-resistance, obesity, and dyslipidemia, which are the main features of the metabolic syndrome (MS). NAFLD and MS are often seen in the same individual, and it has been reported that nearly 90% of the subjects affected by NAFLD, have more than one component of metabolic syndrome . You can learn more about NAFLD at the SuppVersity 6 Bananas A Day = No Problem For the Liver! Can We Blame NALFD on Fructose? Insulin Sensitivity is Determined in the Liver Saturated Fat & NAFLD - Is there a Link? Snack ...
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More Evidence that Too Much Fish Oil (5g+ of EPA + DHA) Increases Inflammation + May Promote NAFLD | Confirmed: Bioavailability of Krill Oil > Fish Oil - Implications?

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There's something fishy about high dose fish oil supplementation. Increased inflammation and beginning fatty liver disease clearly indicate that the dose-response curve for EPA + DHEA is U-shaped. Meaning: More doesn't help more! Don't worry! I am not going to tell you that you have to drop your beloved fish oil supplements altogether. Next to making sure that they are not filled with unwanted Persistent Organic Pollutants (POPs | learn more in a recent SV article), though, the results of a recent stuy by researchers from the University of São Paulo , the University of Southampton and the Campus Universitário in Londrina should remind you that "more does not always help more". Against that background, I am not sure how relevant the increased bioavailability of krill vs. fish oil actually is in terms of the desired beneficial effects your supplements are supposed to have on your health. In spite of that, I would like you to know that European researchers h...
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What's Worse for Your Body Composition & Liver Health? 10g of Sugar from Coke or the Same 10g From Cookies? Plus: Liquid Sucrose is Harder on the Liver Than Fructose

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Hard do believe, but the 10g from coke may actually do more harm than the same amount from cookies. If you want to scare me away from a discussion about the "fat problems" the US and large parts of Europe are struggling with, you just have to repeat Taubs'ian statements such as "if we had not eaten carbohydrates all the mess wouldn't have happened." It's certainly true that the exorbitant and mislead carbohydrate intake and the psyochological consequences ("Fat is bad, isn't it?") of the "low fat" decades from the 1970-1990s is part of the problem, but when we look closer, it's not as simple as to say "we don't eat enough fat". As Yvonne Ritze and her colleagues from the University of Hohenheim , the Technische Universität München , and the Interdisciplinary Obesity Center in Rorschach (Switzerland) write in their latest paper in PLoS One , it's rather the unhealthy conglomerate of "changes in ...
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Dietary Fructose vs. Endogenous Fructose Production: Is The Aldose Reductase Mediated Production of Fructose to Blame for Diabesity & NAFLD? Plus: Could Amla Help?

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Make you choice - cholesterol and regular sugar (left), or fat free and fructose-laden? In the end it all may not even matter. When I stumbled upon a recent study from the University of Colorado a few days ago, my first thought was: Oh my! That sounds familiar. And indeed, if you know anything about the "cholesterol conundrum" you will probably feel reminded of the disconnect between cholesterol intake, cholesterol levels in the blood and cholesterol-related increases in cardiovascular disease risk - don't forget that this is still an issue, although it may neither be your dietary cholesterol or your total cholesterol levels that mediate the risk increases. Looks like you cannot pick your poison, because whatever you chose, your body will produce what it considers fitting from it According to the said study from the University of Colorado it does in fact seem that our current favorite villain, namely fructose, has more in common with its predecessor on the throne...
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High Fish, Soy, Lard & Low Fat Diets: How Do They Affect Body Composition, Lipid and Glucose Metabolism? Results From Study on Rats That Don't Get Obese on High Fat Chow

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(Un!)Surprising results: The "healthy" soy oil is the only fat in the study at hand that causes NAFLD. I know, it is not certain whether or not the results of rodent studies will transfer to human beings and believe me, I would rather have seen this study conducted on humans or at least pigs. And while the latter are simply to expensive, the former are unreliable and don't like to be caged in metabolic wards... well, unless they receive a monetary compensation that costs about as much as a whole pigsty ;-) That being said, let's stick with what we have and take a look at the results, Yoko Hashimoto and her colleagues published in a recent issue of the medical journal Lipids (Hashimoto. 2013). The "obesity resistant" wistar rat and it's reaction to different dietary fats I promise, the results are interesting and probably highly relevant, because the strain of Wistar rats (Slc:Wistar/ST) used in this study does not become obese simply because...
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Iodine Induced Reduction in Hepatic Deiodinase Activity Leads to Hypothyrodism and the Accumulation of Liver Fat That May Eventually Pave the Way to Diabesity

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While us Westerners think of goitre mostly as a result of iodine deficiency, the Chinese have learned by hard that the opposite is about as likely - goitre in response to iodine in the drinking water is a huge health problem in certain parts of the country (Zheng. 2000) As colorful as the web may have become, it is still full of paradigmatic black-and-white thinking: The world is either black or white and if you browse the blogosphere, it would appear that iodine would certainly belong to the white part of our world. That in exactly those people who are often referred to as an example of the multitude of beneficial health effects, namely the Japanese, a high intake of iodine has repeatedly been shown to be associated with low thyroid function and even full-blown hypothyroidism, on the other hand, is something you will probably not learn from the tons of unreferenced stuff you'll find on the Internet about how good, if not essential it was for your health to take copious amounts...
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