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Science Round-Up Seconds: Breast Cancer, GH Induced Insulin Resistance, Stretch + Contraction Increase Molecular Hypertrophy Signals and Probiotics & the Obesity Pandemic

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When we are talking about the extinction of endangered species such as the Siberian tiger, we are adopting a perspective that will also help us to understand such things as the pitfalls of probiotic supplementations as a "solution" to the diabesity epidemic It's Friday the day after the SuppVersity Science Round-Up ( download the podcast ) and you all know what that means: Right! Time to summarize the stuff that did not make it into the show and provide you with a couple of thoughts, as well as additional information on the topics, Carl Lanore and I did already cover (this does also imply that you have to listen to the show if you want the info on the genetic and non-genetic underpinnings of breast cancer). If I had to come up with a motto, something that connects the topics in the show and thus obviously also the ones that will be discussed in this article, I guess it would be "ecosystems". I have repeatedly pointed out in the past that I am not a beli...

Yes, Skin Bursting Pumps Will Make Your Muscles Grow

Arnold already knew: "If you want to grow, go for the pump!" A recent study by Soltow et al. ( Soltow. 2010 ) expands on Arnold's hypothesis - what you need is pump and stretch . The scientists studied the effect of nitric oxide (NO) on C2C12 myoblasts and found: NO, COX-2, and NF-kappaB are necessary for stretch-induced proliferation of myoblasts. Although COX-2 and NF-kappaB are both involved in basal proliferation, NO does not affect basal growth. Thus, NO requires the synergistic effect of stretch in order to induce muscle cell proliferation. So, more NO, some stretch and / or skin bursting pumps? That reminds me of the good old first generation pump supplements with arginine, of which I can only repeat do not dump your good old NO Xplode , White Flood , Super Pump 250 , VPX Shotgun , etc. down the toilette. It is not for nothing that they have been around for years! What's more, Arginine and Ornithine (ingredients of the first generation Pump Supps) ha...
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