Sleepless Nights: Are Pre-Workouts and A Huge Cup of Coffee Messing With Your Sleep? Plus: 5h Half-Life & 15h Clearance Time Caffeine Stays

This couple probably didn't have a two huge cups of high-caffeine coffee with 400mg caffeine, each, before bed ;-) The recent publications of a paper by Drake, Roehrs, Shambroom and Roth in the Journal of Clinical Sleep Medicine woke my interest in the quantitative and qualitative significance of the potential negative effects coffee / caffeine can or will have on sleep (Drake.2013). In the experiment, Drake et al. describe in their latest paper, the researchers made (much to my surprise) a first attempt "to investigate the relative effects of a given dose of caffeine administered at different times of day on subsequent sleep." (Drake. 2013) Fixed dose (400mg) + varied times To do so, Drake and his colleagues from the Sleep Disorders & Research Center at the Henry Ford Hospital and the Department of Psychiatry and Behavioral Neurosciences at the Wayne State College of Medicine , in Detroit, as well as a scientist who worked for Zeo Inc in Newton, compa...