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Forskolin: Friend or Foe? Stories and Studies About Fat Loss, Lean Gains, Topical Cellulite Treatment, Testosterone, Cancer, Hepatotoxicity, Drug Interactions & More

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There is a single human study that would suggest that forskolin would make you get closer to this classic physique w/out tons of salad (who said that's necessary anyway?). Since Maxim asked in one of his more recent comments about the usefulness and/or downsides of forskolin, I dediced to dedicate this Sunday (finally again?) to answering a user question and am going to briefly sum up some older and the few novel findings on forskolin I am aware of. For those of you who find that boring: Don't blame Maxim alone, another reason for this decision was that I have seen discussions on forskolin resurface elsewhere on the Internet. By the way, I write re-surfaced, because forskolin has once been hailed as a testbooster and fat loss adjuvant, but as the prices increased and people came out with faked or low-quality products that did not yield results, the market collapsed. What is forskolin and where does it originate from? As usually there is more than a single answer to t...

Cirsimarin: An Almost Completely Overlooked Lipolytic Agent

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It is interesting that, with the exception of USP Labs , who happen to have a talent to find "unorthodox" ingredients for their products, no supplement company has yet sourced an extract from Microtea debilis . After all, a similar extract ("similar" to the one used in USP Lab's Recreate ) was found to exert strong lipolytic properties being 20 times more potent than caffeine in a 2005 study by Girotti et.al. (cf. Girotti, 2005 Fig.1, below) Although the mechanism of action has not yet been fully investigated, a previous study by Hasrat et.al. found an antagonistic interaction with adenosine receptors similar to that of caffeine ( Hasrat. 1997 ). The exact effect of Cirsimarin differs however from that of caffeine and the less pronounced effects Gingko biloba, so that the researchers conclude: "This suggests that [...] the lipolytic activity of cirsimarin is related to another mechanism. [...] Studies to identify the precise mechanism of action of cir...
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