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Resistant Starch (RS4) Reduces Waist Circumference, Body Fat % & Cholesterol Levels in Lean and Obese Individuals in Randomized, Double-Blind Cross-Over Human Study

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Effortlessly lean with RS4? Probably not, but if you're into flour-based products it may be for you. Some things are resistant to being forgotten. D-aspartic acid, for example, is useless and still around. RS-4, on the other hand, has more or less disappeared from the market, when Scott Connely's and Vince Andrich's last project Myotropics shut its doors. What? Oh, you don't even know what I am talking about? Well, RS-4 stands for "resistant starch", type 4. It's usually made from waxy maize starch, but will - due to its unique structure pass through the gut, more or less undigested ( learn more ). RS-4 will thus end up in the long intestine, where it is eaten up and being fermented by your bacterial subtenants to eventually be absorbed by your gut in the form of short-chain fatty acids - readily available energy with a metabolic twist - a twist due to which they will also function as signalling molecules in the complex concert that is your metabol...
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Ramp Up Your Short-Chain Fatty Acid Production With Fermentable Starches Within 6 Days. Longterm Fat Loss, Gut Health & Cancer Protection Possible

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You cannot handpick several billion lodgers in your intestine, but you can attract the right one by providing them with the foods they like. Contrary to the current probiotic hype, the key to gut and metabolic health lies in the prebiotics you are stuffing down your piehole. It's quite funny, only 5 years ago, everyone was still smiling at people who spent extra bucks on yogurts and other dairy products that were enriched with certain bacteria strains - strains, which were and obviously still are supposed to have health-promoting effects. The fact that probiotic yogurts and similar stuff have meanwhile made it into the store brand line-up of the large discount-markets (at least here in Germany) is however clear cut evidence that the previously laughed at idea that gut bugs are something you want to foster and promote has meanwhile turned into another of those partly highly questionable, but widely accepted pieces of "nutritional wisdom". The question that remains is, ...
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Vitamin A Regrows Liver Tissue. Polydextrose Makes Dieting a Breeze. Exercise Blunts Negative Effects of High Fructose Diet. Diabetes Precipitates Female Sexual Dysfunction.

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I did miss my own 1000-posts jubilee! This week it's pretty easy to find the SuppVersity figure of the week. It's 1011 and that's the number of individual posts this "blog" currently holds. Actually, the very moment I hit the "publish" button on this one, it's going to be 1012 (see image on the right). I guess, I should have 'celebrated' that twelve posts before, but you know how I am, it's about the quality, not the quantity and though I am aware that the latter is unquestionably fluctuating, I would hope that each of you has found one or two 'pearls' - I mean, if you didn't why are you coming back regularly, then? Apropos regularly, it's Saturday and thus about time for a couple of "On Short Notice" items. So let's not waste any time flattering and get to the science news business: Vitamin A essential for liver regeneration. Plus: β-carotene and cancer even in non-smokers So much for the vitami...
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Shedding Some Light on the Leaky Gut <> Exercise Connection. Plus: 20+ Things You Should or Shouldn't Do to Protect and Restore the Integrity of Your Intestinal Wall

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Have you ever felt nauseated after a workout? Or does your protein supplement gives you diarrhea only if you take it right after a workout? Both can be related to the toll  exercise can take on the integrity of your intestinal tract. To be honest, I was quite surprised that I did not get a hell lot of hatemail in response to the the 'MSG heals the gut study' I posted last Sunday ... Be that as it may, I feel sort of awkward to have opened Pandora's box without proving you with some betters tools than mono-sodium glutamate (MSG) to seal the box, or rather your leaky gut, again. Therefore I decided to post this mini-feature on a particular issue all of us will be dealing with: An exercise induced increase in gut permeability. As you are going to see, there are a lot of similarities to the 'classic' leaky gut, which is often implicated in the etiology of chronic inflammatory bowel diseases. In order to understand these similarities, but also the few, yet importan...
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Saturated Fat Kills Gut Bacteria & Modifies Genes in the Distal Small Intestine - Another Reason Why We Get Fat? Plus: Bacteria, Fiber, SCFA, GLP-1 & PYY Revisited

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Image 1: Bacteria, there are >100 trillion of them right inside of your digestive track, you can hardly know them all and scientists do neither - the only thing we are beginning to understand, though, is that it may be a good idea to get them to know at least somewhat better ;-) I guess some of you have already noticed that I was (and probably am now, again) somewhat behind, as far as answering your questions, comments an wise remarks are concerned. Actually it is still more of a coincidence that today's SuppVersity news, which, as you see is not an Adelfo Cerame post (don't forget to keep the fingers crossed for him! This is his weekend!), could actually be interpreted as my somewhat lengthy response to a comment from Vincente on the effects of GLP-1 on chocolate preference in rats and an interesting hypothesis of his, on how this could all relate to my previous post on the fat burning effects of GLP-1 (" Eat More, Burn More and Lose Fat Like on Crack with GLP...
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Eat More, Burn More and Lose Fat Like on Crack with GLP-1!? Roux-en-y Bypass Study Sheds a Whole New Light on Satiety(Hormone)-Induced Weight Loss

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Image 1: A gastric bypass should always be the last option; with all the possible complications it is nothing to treat lightly (img medcenterone.com) Everyone who has read the Intermittent Thoughts on " Goal Setting and Programming Success " with the three somatypes, SuperSize Homer, Peter Griffin and Anorexic Stan, will be aware that I do acknowledge the oftentimes life-saving benefits of surgical anti-obesity interventions, when everything else fails. Until recently, I did however assume that"cutting off" a part of your stomach or using a sling or other devices to reduce its size would simply reduce a patients ability to overeat, thusly reduce hi caloric intake and help him to cut his weight back into a region that is no longer life-threatening. The recent publication of a study by scientists from the Harvard Medical School ( Nestoridi. 2012 ) does yet suggest that the effects of roux-en-y gastric bypasses are in fact way more far reaching than, at least I...
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