Posts

Showing posts with the label glutamate

Popular topics

Show more

Glutamate: Can It Be Use To Your Advantage? Study Shows Insulin Sensitizing Effects of Dreaded Food Additive

Written by | published on
Image
"Now you've got me confused!" In the context of MSG scare, glutamate has gotten such a bad rep that it seems highly counterintuitive to assume that there was anything good about the major excitatory amino acid in the human body and still, a recent study from the Department of Kinesiology at the University of Waterloo clearly suggests that "MSG and carbohydrate supplementation can be used to manipulate plasma glutamate" (Sebastiano. 2013)... and no, we are not talking about an in-vitro or rodent study here. With 9 perfectly healthy, recreationally active men aged 23.9+/-1.9y and a BMI of 25kg/m² the results can however be taken as being representative for at least large parts of the ever-decreasing number of "normal-weight" individuals. There is a potential string attached Usually, the "on the other hands", are something I am talking about at the end of the article, but in this case, of which I expect that it's going to become ...
Read full article »

Science Round-Up Seconds: 8 Nootropics to Combat Stroke, Alzheimer's & Co, Boost Cognitive Performance. Plus: 7 Unknown Side Effects of High Dose Glutamine.

Written by | published on
Image
Effects of infusion times on phenol content of black tea (Ramalho. 2012) If you have already listened to the podcast of yesterday's Science Round-Up on the Super Human Radio Website ( click here if you haven't and wan't to know what the following is all about), I suppose you will not mind that I compiled some of the complex information about "optimal" tea brewing in the illustration to the right (based on Ramalho. 2012). The colored arrows indicate the time-points at which the given compounds in the tea achieved peak values. The exact time point is also given in minutes, so that a 9' in front of the green caffeine and on the left to the green arrow pointing at the 9 min point tells you "it took 9 minutes for the caffeine content to reach it's maximum in the British tea". The graph in the background shows the catechin concentration depending on the infusion time. Cholinergenic nootropics - What a recent review says I guess some of you wil...
Read full article »

Mono-Sodium Glutamate (MSG), NAFLD, Leptin Resistance, Trans-Fats, HFCS, Gluttony, Leaky Gut & Brain, the Vagus Nerve and the Chinese Restaurant Syndrome - Bon Appetit!

Written by | published on
Image
Image 1 (msg-exposed.com): Is obesity the inevitable, unnatural metabolic long-term equivalent of the dreaded "Chinese Restaurant Syndrome"? Earlier today, I posted a blurb from a recently published epidemiological study on the effects of mono-sodium glutamate, aka MSG, an umami = all taste receptor activator that is commonly found in all sorts of ready made foods that would otherwise taste as lame as their individual fake ingredients, on the SuppVersity facebook wall (Insawang . 2012). The scientists had evaluated the data from 324 families (349 adult subjects, age 35–55 years) from a rural area of Thailand and found that the prevalence of metabolic syndrome was not just significantly higher in the tertile with the highest MSG intake, but that the "odds ratio", i.e. the chance that a certain parameter, in this case "obese, yes/no" would be found to be true, increased with every 1 g increase in total MSG intake irrespective of  the total energy inta...
Read full article »

Use Glutamine to Heal the Gut and Hinder Your Gut Bacteria from Eating Away Your BCAA, Arginine and Other Aminos

Written by | published on
Image
Image 1: Don't do this at home. A pig with cannules that have been dug into its digestive tract to study chemical enzymatic and microbial actions ( University of Illinois ) With terms like "the leaky gut syndrome" and the usual quick (and not so quick) fixes a la "solutions for a leaky gut" being all over the blogosphere, I suspect that I am not telling you anything new, when I say that there is reasonable scientific evidence that glutamine is good for your gut (nice alliteration, by the way ;-). That it is yet also "good" for the bacteria in your gut may be news to you. According to a recently published study by scientists from the Laboratory of Gastrointestinal Microbiology, at the Nanjing Agricultural University in Nanjing, China, dietary l-glutamine can exert direct regulatory effects on the amino acid utilization of your gut bacteria - specifically their uptake and use of l-arginine and related amino acids ( Dai. 2012 ). "Hey, you gut ...
Read full article »

Scientific Evidence Links High Carbohydrate Intake to the Development of Alzheimer's and Other Neurological Diseases

Written by | published on
"Fats are bad, carbs are healthy!" I hope nobody out there still believes this late 20th Century slogan. If you do, chances are you will soon forget about it due to the neuronal damage you are inflicting to your brain by eating a high carb diet. In a very recent review, a group of international scientists ( Seneff. 2011 ) summarize the current state of research as follows: [...] an excess of dietary carbohydrates, particularly fructose, alongside a relative deficiency in dietary fats and cholesterol, may lead to the development of Alzheimer's disease. A first step in the pathophysiology of the disease is represented by advanced glycation end-products in crucial plasma proteins concerned with fat, cholesterol, and oxygen transport. This leads to cholesterol deficiency in neurons, which significantly impairs their ability to function. Over time, a cascade response leads to impaired glutamate signaling, increased oxidative damage, mitochondrial and lysosomal dysfu...
Read full article »

L-Ornithine HCL as an Ammonia-Buffer for Hard Training Athletes

Written by | published on
Image
Figure 1: Chemical structure of L-ornithine (HMDB v2.5) Habitual readers of the SuppVersity will be familiar with the ergogenic effects of l-ornithine . A recent study by Demura et al. ( Demura. 2010 ) verified the immediate effect of l-ornithine supplementation on ammonia and glutamate metabolism. In their 14 healthy young volunteers, who trained regularly , the scientists observed significant increases in plasma ammonia and glutamate upon supplementation of 0.1.g/kg body weight before the subjects conducted incremental exhaustive ergometer bicycle exercises. Interpreting their results as follows, although the ingestion of L-ornithine hydrochloride before the exercise cannot be expected to improve performance, it does increase the ability to buffer ammonia, both during and after exercise , Demura et al. are yet reluctant to postulate a direct effect on exercise performance.Such an effect has however already been reported in the 2008 study by Sugino et al. , I already referre...
Read full article »
Disclaimer:The information provided on this website is for informational purposes only. It is by no means intended as professional medical advice. Do not use any of the agents or freely available dietary supplements mentioned on this website without further consultation with your medical practitioner.