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Alanyl-Glutamine or Alanine + Glutamine? Dipeptide or Free Form Aminos? What Offers Maximal Muscle Protection?

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"Wouldn't have happened if she'd used alanyl-glutamine instead of regular that cheap alanine + glutamine combo!" - True or False? Recent study says: False! If you combine your liver's favorite gluconeogenic amino acids, i.e. alanine and glutamine, into a single peptide the result is called alanyl-glutamine and marketed as the ueber-potent alternative to regular l-glutamine supplements. It goes without saying that a comparison like this is about as stupid as comparing french fries with mayo to regular french fries and saying that the former are worse because they contain more fat, or whatever. Even if we didn't care about the physiological significance of the effects of alanyl-glutamine, we would obviously have to compare the purported cryogenic effects of this "innovative" dipeptide to those of a simple combination of free form amino acids to deserve the bragging rights for having created an advanced form of glutamine. Alanine + glutamine vs. a...
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New Role for Glutamine in Protein Synthesis? Study Suggests Direct Effects on Mammalian Target of Rapamycin (mTOR) - EAAs Alone Won't Produce Optimal Results

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Image 1 ( Pumping Iron ): The guy in the middle, obviously no one else than the Austrian Oak, took glutamine, the rest of the guys forgot about it in all the craze about leucine... no, just kiddin' ;-) Still, someone who trains like Arnold, is probably most likely to benefit from additional l-glutamine After all those bad news about allegedly effective supplements, I thought it may be about time to present some good news about an allegedly ineffective supplement: Glutamine! Published ahead of print in the online version of the scientific journal Amino Acids , the results from a 2012 study by Martina Chiu and her colleagues from the Unit of General and Clinical Pathology at the Department of Experimental Medicine of the University of Parma in Italy (Chia. 2012), could well explain a recent comment by Macijec who recounts that he saw great improvements in lean-mass retention on a diet from a combined BCAA + glutamine supplement over taking just plain BCAAs. And while I will get...
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