MTHFR Mutations, Cardiovascular Disease, and Riboflavin (B2): Scientists Zone in on a Neglected Ménage à Trois
You can test your MTHFR gene either directly or by plugging your raw data from 23andme, or another provider into evaluation tools such as Genetic Genie . If you have no idea what #MTHFR means, here's the Reader's Digest version: MTHFR is an enzyme that is affected by a mutation in the MTHFR gene. The latter encodes the enzyme methylene-tetrahydrofolate reductase a ka MTHFR effectively unless there's a single-nucleotide polymorphism (SNP) affecting the 677th base pair of the MTHFR gene... not helping? Well, let's just say if you have a certain variation of this gene, you're having a hard time processing B-vitamins; and it's not totally unlikely that you're affected : According to Marini et al. 2008 , this mutation affects 29% of the global population. Previous studies, however, report much lower estimates for prevalence of the MTHFR 677TT genotype, i.e. 10% worldwide, with values ranging from 4 to 18% in the United States, over 20% in Northern China to ...
