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Blocking Inflammation is Like Choking the Fire: Long Term Weight-, Visceral- and Android-Fat Gain in Human Study Emphasizes Essential Role of TNF-α in Metabolic Control

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Can cooling down the inflammation make your belly grow!? (Mito-)Hormesis and the important and beneficial role of "inflammatory" cytokines, molecules etc. are one of my favorite topics. It's simply intriguing that health, performance and longevity apparently depend on the presence of a healthy amount (whatever that may be) of inflammation. Even the provision of low dose arsenic does not - as you may expect - shorten, but prolong the lifespan of several common model organisms (Schmeisser. 2013). Findings like these don't just conflict with common sense, they are also in opposition to the still prominent free radical theory of aging and it's central message: Oxidation and inflammation are bad for you! No matter what!  Too little is just as bad as too much Most of you will remember one of my previous articles on (mito-)hormesis - if if that's not the case, I'd recommend you start with the "Inflammation is a True Fat Burner" article ( re...

Pomegranate for Prostate, Rheuma, Breast Cancer, Aromatase, Obesity, Diabetes, Inflammation, HIV, Influenza, Herpes, Crohn's, Hepatitis, Infertility ... You Name It!

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Image 1: This drawing from a German 1885 compendium on the flora in Germany, Austria and Switzerland shows that other than Acai & Co, pomegranate is no exotic (expensive and useless) discovery of some fly-by-night supplement vendor. People are always all the rave, when some clever scientist (or should I say business man?) dug up another of those exotic fruit from a godforsaken valley somewhere in the African or South-American primeval forests. With the hype around ACAI & Co they often forget that there have been real Superfoods just around the corner, right in their local grocery store for years. Pomegranate, as it becomes increasingly evident from recent research, is one of these Superfoods - one that has even been mentioned in the Book of Exodus and has been part of the Ayurevedic tradition for centuries, now. While I have been following the research for some months now, the one mind-boggling study result has always been missing so that this is in fact the first blogpos...
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