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The Vampire Approach to Longevity - Young Blood Revives Muscle, Brain & More | Plus: 6+ Less 'Horrific' Alternatives

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Download the podcast this article relates to at superhumanradio.net You will probably remember from the SuppVersity  Facebook news (@SuppVersity |  March 15, 2018 ) that scientists believe that they've found the molecule that's responsible for the rejuvenating effects of "young blood". In their study, which expanded on rodent data indicating that the injection of "young blood", i.e. blood from young mice, into the circulation of old(er) mice has multi-dimensional rejuvenating effects, the researchers grew  human  muscle cells (C2C12 myoblasts) in a petri dish and stimulated them w/ media conditioned with 5% plasma from healthy male participants that were either younger (n = 6, 18–35) or older (n = 6, >57 years). What Kalampouka et al. ( 2018 ) observed was that the muscle cells reacted differently to a stimulus in form of a scratch (intended to simulate muscular injury and recovery) depending on whether the cultured in media conditioned plasma from ...
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Overeating = Natural Response to Strict Dieting That Occurs Despite Increased Satiety Hormone Response to XXL-Meal

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This is not a photo from the full-text of the study, but it could be. After all the energy deficient diet was >90% below the maintenance intakes of the subjects. That's unfortunately much more severe than the average dieter's approach, but some of the things the scientists observed still have very general applications. If you've ever dieted to make the cut in a sports with weight classes, you will know this insatiable hunger which climaxes on the last two days when you are down to a handful of  calories per day. It's a hunger that won't be satisfied even if you eat an extra 1000 kcal above maintenance. Athletes competing in sports with weight classes may need to accept the post-dieting binge, but what about average Joes and Janes? Will a fasting day ruin the average dieters dieting efforts by making them eat more extra-calories on day 2 than they've economized the day before? A recent study from the  US Army Research Institute of Environmental Medicine ...
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Resistance Training, Not Starving Yourself or "Cardio" is Key to Successful Fat (!) Loss -- Metabolic Stress Appears to Determine Improvements in Body Composition & Health

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Just look at the guys surrounding you, girls. How on earth will you get bulky if they are training like maniacs and still look like size-zero bans? "Overfat", that's a term scientists use to refer to obese, but more importantly over- or even normal-weight people who are still carrying exuberant amounts of body fat around. In a recent meta-analysis, James E. Clark from the Manchester Community College tried to figure out, which of the significant numbers of means of methods to alter body composition, and metabolic issues that are available for the adult who is overfat is the "best" one. In his review, the scientists focused on comparing changes from treatment program for adults who are overfat based on analysis of aggregated effect size (ES) of inducing changes from 66-population based studies, and 162-studywise groups. Learn more about dieting and not ruining your metabolism @ www.suppversity.com Orgasm Hormone Increases REE 9 Tricks to Keep You R...
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True or False? Losing Your Weight Slowly Will Yield Better (Long-Term) Results Than Rapid Weight Loss - Another Common Weight Loss Myth Debunked by Science?!

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With adequ. protein and nutrients "crash"- beats "low and steady" -dieting. In the obese that's almost certain, in athletes more experimental evidence are needed. You will have heard and read that rapid weight loss will make you lose muscle and set you up for weight regain aka the " Yo-Yo effect ". As a SuppVersity  reader, you know that things are not as simple as that. While some studies appear to support this urban myth others suggest that the exact opposite may be the case. A 2014 study by Purcell, Sumithran, and Prendergast that was published in the venerable scientific journal The Lancet  for example, showed that rapid weight loss on a very low calorie diet leads to better long-term outcomes than gradual weight loss on a much less restricted diet. You can learn more about improving your body composition at the SuppVersity Long-Term Dieting Makes Gymnasts Fat! Minimal Carb Reduction, Max. Results? HIT Circuit + Plyos for Glu...
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