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Hair Loss: Finasteride, Laser Light or Minoxidil - What Will Really Help Men & Women Regrow Lost Scalp Hair?

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Men may be at a higher risk, but androge-netic hair loss is not a male exclusive. Minoxidil, Finasteride, and low-level laser light therapy are Food and Drug Administration-approved/-cleared treatments for androgenetic alopecia, but do they actually work? That was one of the questions Areej Adil and Marshall Godwin tried to answer in a recent review; a systematic review and meta-analysis the scientists from the  Memorial University of Newfoundland  published in the Journal of the American Acadamy of Dermatology very recently and a paper of which its authors claim that I will clear up the confusion about the seemingly conflicting results of individual studies. If your scalp is not your weak area, try these exercise to shed fat and gain muscle . Tri- or Multi-Set Training for Body Recomp.? Alternating Squat & Blood Pressure - Productive? Pre-Exhaustion Exhausts Your Growth Potential Full ROM ➯ Full Gains - Form Counts! Battle the Rope to Get Ripped...
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Dustasteride Doesn't Hamper Mass & Strength Gains on TRT, but Compromises the Fat Loss Effects of Testosterone and Does Not Reduce Any of the Side Effects

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Image 1: I guess after the publication of his latest study, Mr. Bhasin will have a bad standing with the pharma reps from GlaxoSmithKline & Co ;-) What happens if you take a couple of healthy guys and put them on a cycle... ah, pardon, I mean, "put them on hormone replacement therapy"? Assuming that you have paid attention in the seminars of the Intermittent Thoughts Series on Building Muscle (cf. " Preliminary Conclusion + Summary "), particularly the part " Quantifiying the Big T ", it should not be difficult for you to answer: The guys will gain a few slabs of lean muscle mass! But what would happen if you added in some finasteride , or it's uber-potent cousin dustasteride ? Will you gain more or less? Will you be protected from acne and prostate growth? The "Big T" as in "Testosterone" or as in "Taboo"? As an MD you are not supposed to ask these questions... you are not even supposed to put your male patien...
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Intermittent Thoughts: Dihydrotestosterone (DHT) - Bigger, Stronger, Faster or just Balder, Fatter and Unhealthier?

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Image 1: The ancient Greek ideal of the male body has probably more to do with DHT than the freaky physiques of today's IFBB Pro bodybuilders. I guess after the revelations about the importance of estrogen in the process of skeletal muscle hypertrophy in the last installment of the Intermittent Thoughts you will probably be eager to hear what its male counterpart dihydrotestosterone (DHT), is able to do... I mean, with DHT being the male hormone par excellence it is only reasonable to assume that its effects on skeletal muscle mass and strength, two characteristic features of the male persuasion, must be significant, right? Before we are going to address this vitally important questions, let's briefly take a look at what the dihydrotestosterone actually is. DHT the hormone to which testosterone is just another prohormone Similar to estrogen, DHT (exact name 17β-hydroxy-5α-androstan-3-one ) is a testosterone metabolite. The process by which your body (male and fema...
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Problems with High or Low DHT? Use Rice or Safflower to Inhibit and Sorghum to Promote 5-Alpha Reductase!

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Image 1: High or too low DHT levels? Nature has the cure for both. Lower your DHT levels with rice bran or safflower flower extracts or raise it with a crude extract from Sorghum bicolor seeds. Hairloss for men, and even more so for women, is certainly one of the nastiest side effects of either naturally or artificially induced hormonal disturbances. And while the vilification of DHT as the #1 inducer of male pattern baldness and a potential cause of female hair loss may be overblown, it is a well-established fact that (over-)expression of DHT, or rather a high / over-activity of the 5a-reductase enzyme which converts testosterone to the ~10x more potent androgen dihydrotestosterone will, over time, lead to a shrinkage and gradual disappearance of affected hair follicles . In that, it is noteworthy that similar to the carcinogenic effects estrogen exerts on female (and male) breast tissue, it is mostly the local and not so much the systemic reduction of testosterone to DHT, or, in...
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Now Its Official: Propecia Drug Finasteride Kills Male Libido Permanently

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Image 1: Chemical structure of finasteride Other than the FDA some European medicine and health care agencies, such as the Swedish Medical Products Agency and the Medicines and Healthcare Products Regulatory Agency of the United Kingdom already had the guts to declare in their patient informations that " persistence of erectile dysfunction after discontinuation of treatment with Propecia has been reported in post-marketing use. " While this was obviously no reason for the all-mighty FDA to correct or re-evaluate their own documents, two it did intrigue Michael S. Irwig and Swapna Kolukula, two US scientists from Washington and Baltimore, respectively. In their study ( Irwig. 2011 ), the scientists conducted standardized interviews with 71 otherwise healthy men (age: 21–46y), who experienced permanent (>3 months) sexual side effects after temporary use of Finasteride. Their reports are staggering: 94% developed low libido , 92% developed erectile dysfunction , 92% d...
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Positive/Negative Effects of Normal/High DHT on Metabolic Pathways

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Regular visitors of the SuppVersity will certainly remember some of my previous posts about the false demonization of DHT. A new study coming from the Institute of Endocrinology in Prague ( Duskova. 2010 ) supports the view that "optimal" and not low DHT levels are what men should be striving for. Theorizing that DHT as a non-aromatizable androgen could be responsible for a male type fat distribution, the scientists reviewed the results of both animal and human studies and found that " physiological levels of DHT [do not only] inhibit growth of mature adipocytes ", but also have positive levels on body composition in patients on hormone replacement therapy (HRT). On the other hand, there is also evidence that high (super-physiological) DHT levels are associated with obesity: In obese people, DHT metabolism in adipose tissue is altered. Local abundance of non-aromatizable androgen has a negative effect on adipose tissue and it could be involved in pathogene...
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Is DHT Really the 'Bad and the Ugly'?

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Fellow men, common (bro-)science tells us that dihydrotestosterone (DHT, molecular structure see image on the right. HMDB ) will make your hair fall out and trigger cancerous growth of your prostate. Current research, however, suggests that Estrogen might just as well be the real culprit when it comes to unwanted growth a few inches above your testes. This is, as Williams (2010) phrases it, part of a "controversial break-through" achieved by scientists in the course of the last months and the results of which he sums up as follows: "The synergistic action of unopposed oestrogen and leptin , compounded by increasing insulin, cortisol and xeno-oestrogen exposure directly initiate , promote and exacerbate obesity, type 2 diabetes, uterine overgrowth, prostatic enlargement, prostate cancer and breast cancer ." It was thus certainly no bodily injury caused by negligence, when Konnelius et.al. 2002 administered 125-250mg transdermal DHT to 60 subjects (age range, 50...
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