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Complete Meals & GI (Non-)Sense, Glutamine & GLP-1, Low Thyroid & High Trigs, N-3 vs. N-6 Interactions, Optimal DHA Dosage in Kids W/ NAFLD, Selenium vs. Aluminum Toxicity

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While this is not the exact combination of chicken breast, mashed potatoes and salad in the first one of today's news items, it's more than likely that the predicted GI (and thus probably what you would find if you looked it up in a table) overestimates the postprandial glucose response to this meal by ~50% and says absolutely nothing about the insulin response. It looks like complex meals and over-simplified theories, don't mix well, at all ;-) 78% that's the SuppVersity Figure of the Week and actually part of the additional information I provided on one of today's On Short Notice items. It's the increase in coronary heart disease risk women with subclinical hypothyroidism have compared to their peers with spot on TSH levels of 0.5-1.5mU/L (Asvold. 2012). In conjunction with other more or less recent studies, such as Mitchel's, Hsu's and Sahai's paper confirming the previously often talked about but not well-established 2-fold increase in con...

Eat Right to Burn Fat: Low Carb Meal Before Workout Shifts Substrate Utilization During Exercise More Towards Fatty Acids

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In view of everything, you as regular visitor of the SuppVersity have learned about nutrition and exercise science, you probably would not need the results of the following study, to know better than to consume a sugary pre-workout drink, if your main goal is to lose fat and get ripped. Just in case, however, your friends or relatives belong to the group of unconvertible carbohydrate addicts, who still (want to?) believe that "fat burns in the fire of carbohydrates", printing this blogpost and sticking it to their gymbag may in fact turn out to be a "fat burning" endeavor... Figure 1: Respiratory Exchange Ratio (RER) following the consumption of a  low carb (LC) or low fat (LF) mealt; remember: a lower RER is associated with a higher percantages of fatty acid oxidation / lower carbohydrate oxidation (data adapted from Gregory. 2011 ) Sara Gregory and her colleagues from the Department of Exercise Science and Sports Studies at Springfield College recently publ...

Effects of Macronutrient Composition on Metabolic Signaling: Higher Protein Diet Favors Glycogen Storage in Muscle Over Adipose Tissue

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Those of you who have already listened to the latest, revamped (and improved) episode of Dr Scott Connelly's BodyRx Show will already have heard of Suzanne Devkota's and Donald K Layman's study ( Devkota. 2011 ) on the effects of different meal compositions on the postprandial glucose disposal. For the rest of you who have missed the episode and those of you who like their info white-on-black, here are the main results... For 10 days, Devkota and Layman fed 60 rats a diet containing either 60% of energy from carbohydrates, 12% protein, 28% fat (CHO) or 35% carbohydrate, 35% protein, 30% fat (PRO) and evaluated plasma levels of insulin, glucose and C-peptide , as well as muscle and adipose tissue Akt, p70S6K and Erk 1/2 (markers of glucose and protein metabolism and cellular growth, respectively). The graphs in figure 1 illustrate their most significant finding quite nicely. Other than in the case of the protein-fed rats, blood glucose is preferentially stored in...
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