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Cyclists & Asthma? ~20% Increased Protein Synthesis W/ Salbutamol, Another Reason its Abuse Cannot be Ignored

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Even if it is medically indicated, there's more and more evidence that using beta-2-agonists (esp. but not exclusively orally) could provide an unfair advantage to athletes: increased protein synthesis, increased mitochondrial neogenesis, established ergogenic effects,... If you've been following the news, you will be aware that the Tour de France Champion, Chris Froome, has been busted with elevated levels of the beta-2-agonists  Salbutamol  in his blood ( learn more ). Now, we could debate forever about whether the green light Froome just got is a case of double-standards or not, but that's not the purpose of this article, anyway. Rather, I want to explain why the claim that salbutamol, officially an asthma medication, wouldn't be a worthwhile doping agent is bullshit. Learn more about Clen - / Albuterol  and safer ways to get jacked at the SuppVersity Albuterol Can Improve Glucose Metabolism The Myostatin <> Clenbuterol Connection Higenamine Use...

Albuterol / Salbutamol Doping Works! Cyclists Just Have to Take One Pill For a 4.1% Increase in Peak Power. Plus: Its Chronic (Ab)Use Makes Their Training More Efficient

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Inhaling salbutamol, which is the most appropriate way to combat asthma, will not provide the same beneficial effects to athletes as taking a much higher doses pill and thus "going systemic" will (Norris. 1996; Koch. 2013) Salbutamol (INN) or "albuterol", as it is called in the US, is a short-acting β2-adrenergic receptor agonist. Just like its longer-acting brother clenbuterol, it has been developed to be used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease; and just like its brother clenbuterol, it has been and still is abused by athletes all around the world as a doping agent. For good reasons? Well, a recent study from the University of Copenhagen would suggest just that. After all, the scientists from the Department of Nutrition, Exercise & Sports , Section of Integrated Physiology found acute and long(er) term beneficial effects of salbutamol (ab)use on peak power in their subjects, 20 male endur...

Chronic Albuterol Treatment Improves Glucose Uptake in Skeletal Muscle: Could Your Beloved Coffee Do the Same?

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Image 1: If there is a connection between asthma and diabetes, it probably isn't related to the use of beta-2 agonists. What is one of the most dubious ailments among professional athletes? Asthma, right! Asthma is much better than the meat in Lenny Paul's bolognese of which he claimed that it must be responsible for the nandrolone the WADA officials found in his bloodstream 1997. I mean, even if you don't want to say that you used it yourself the truckload of clenbuterol (once used as a standard treatment for asthma) could still be for your poor asthmatic dog like the one professional cylcist, Frank Vandenbroucke, had squirreled away in his house just when the WADA ransacked his house. Now, less than a month after the publication of a study by Hamzeh Elayan, Milos Milic. Ping Sun, Sunir Gharaibeh and Michael G. Ziegler in the Journal of Cellular and Molecular Neurobiology ( Elayan. 2012 ), I suppose that the next top athlete who is going to be busted will probably cla...

Higenamine: PES Introduces New "Fat Burner" to the Market. Potent Thermogenic or Dangerous Stimulant?

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Image 1: The reformulated PES Alpha T2 contains higenamine , alpha yohimbine and 3.3-diiodo-l-thyronine I just received an advertisement email containing some information about the reformulation of PES popular fatburner Alpha T2 (make sure to read " T2 a Fat Burner for Bulking? " for some details on the thyroid stimulating properties of 3.5-diiodo-l-tyronine the metabolically more active "brother" of the 3.3.-diiodo-l-tyronine in PES Alpha T2) mentioning a compound that is advertised as "an all new beta-agonist", that would have been found to be "more effective" than synephrine. While this claim did not impress me at all, I took the time and dug up some information about "higenamine"... The adrenergic effects of higenamine ( Hig. demethylcoclaurine ) have been well established since the 1980s ( Park. 1984 ). In fact, the cardioactive benzylisoquinoline alkaloid isolated from Aconiti tuber has long been used as a cardiotoni...
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