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Forskolin: Friend or Foe? Stories and Studies About Fat Loss, Lean Gains, Topical Cellulite Treatment, Testosterone, Cancer, Hepatotoxicity, Drug Interactions & More

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There is a single human study that would suggest that forskolin would make you get closer to this classic physique w/out tons of salad (who said that's necessary anyway?). Since Maxim asked in one of his more recent comments about the usefulness and/or downsides of forskolin, I dediced to dedicate this Sunday (finally again?) to answering a user question and am going to briefly sum up some older and the few novel findings on forskolin I am aware of. For those of you who find that boring: Don't blame Maxim alone, another reason for this decision was that I have seen discussions on forskolin resurface elsewhere on the Internet. By the way, I write re-surfaced, because forskolin has once been hailed as a testbooster and fat loss adjuvant, but as the prices increased and people came out with faked or low-quality products that did not yield results, the market collapsed. What is forskolin and where does it originate from? As usually there is more than a single answer to t...

Science Round-Up Seconds: Nicotine's Effect on Brain Aromatase & the Consequences, 2D:4D Digit Ratio Predicts Testosterone Response to Sprinting and All the Anti-Obesity & Pro-Brain Effects W/ Just 2 Cups of Coffee per Week?

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Wallaby Lachie Turner (left), Greg Inglis (centre) & Jarryd Hayne (Stuff.co.nz) - who would have thought that the relative length of their 2nd and 4th digit could predict their testosterone response after the sprint? Not you? Well, then you got to check out the first of the short-items at the bottom. Those of you who have listened to yesterday's installment of the SuppVersity Science Round-Up on Super Human Radio, will have realized that the show did - as usual - take a somewhat different direction than originally planned. Before I get to the actual SuppVersity Round-Up Seconds , of which there actually weren't all too many I consider absolutely newsworthy and appropriate for a written format, I thought I would briefly mention the paper on which I based the hypothesis (remember: this is nothing certain ) that there may be a link between the calcium-influx into the muscle and the strength and hypertrophy effects of performance enhancing drugs (spec. those with a high a...

Endurance Exercise Turns Out to Be More Manly Than You May Have Thought: 30 Minutes on the Treadmill Raise Muscular Dehydrotestosterone (DHT) Levels

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Figure 1: Molecular structure of dihydrotestosterone (DHT) (from Wikipedia) I assume jogging is not what crosses your mind, when somebody is talking about "manly" exercises!? DHT, the acronym for dihydrotestosterone , on the other hand, is what experts like Dr John Crisler (from allthingsmale.com) hold responsible for all things male. So, if, as a recent study ( Aizawa. 2011 ) published in the Journal of the American College of Sports Medicine reports, running on a treadmill for 30 minutes, 5 times a week increased dihydrotestosterone levels in skeletal muscle of male rats, it is pretty likely that moderate jogging can trigger similar hormonal changes in men and thus render them "more manly". What Aizawa et al. found was that an increase in "mRNA expressions of 3[beta]-hydroxysteroid dehydrogenase (HSD), aromatase cytochrome P450 (P450arom) and 5[alpha]-reductase in the skeletal muscle of trained rats" if compared to sedentary controls. These c...
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