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2.5 mg Nicotine = Ergogenic - 18-21% Increase in Power in Crossover Study | Plus: Are Health or Addiction an Issue?

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While cigarettes are neither effective performance enhancers nor safe, nicotine, one of their key ingredients, may be the effective ergogenic aid with a reasonable sides/effects ratio you have been looking for... well, that's at least what the recently published 1st RCT with reliability test and crossover protocol seems to suggest. Yes, nicotine is the main (psycho-)active ingredient in cigarette smoke. It is, however, - and we tend to forget that in the debate about (ab-)using nicotine as a "supplement" - only one out of many "ingredients" of cigarette smoke; ingredients that ruin the health of our lungs and promote the risk of lung and other cancers. It would be haphazard, though, to exonerate nicotine completely, as there is "a direct contribution of nicotine to cancer onset and growth" ( Grando 2017 ). The research on the interaction of individual genetic susceptibility and nicotines ability to activate "nicotinic acetylcholine receptors...
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Role of Muscle and CNS in Diet-Induced Decline of Exercise-Induced Energy Expenditure | Caffeine & Nicotine May Help!

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While "calories count" when it comes to losing body fat, the notion that you would always burn the same amount of energy with a given workout - irrespective of your energy intake - is completely bogus and only one of the reasons why meticulous calorie counting won't work.  Let's address it right away: Yes, the paper Tariq I. Almundarij et al. published in the peer-reviewed journal "Physiological Reports" (Almundarij 2017) deals with a rodent experiment, but  with the goal of the study being to identify the fundamental mechanisms behind, not the extent of metabolic adaptation to calorically reduced energy intakes, this does not disqualify its results as irrelevant for humans - on the contrary (and trust me, I'd prefer a human or at least a pig study, too). With that being said, let's take a look at what the scientists did to "investigate the role of MC4R in the modulation of muscle work efficiency, and test the hypothesis that energy restri...
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True or False: You Can (Ab-)Use Nicotine Chewing Gums to Get Shredded Without Compromising Your Health

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Nicotine gums are made for smokers. Smokers are leaner than non-smokers. Chewing nicotine gums helps you lean out... broscience? Logic? Or bullshit? It's one of the better-known pieces of broscience: "Nicotine chewing gums will promote weight loss!" Aside from being "better-known", it's yet also highly controversial. In that, people usually don't question the fact that nicotine chewing gums may promote weight loss (we do all know that smokers are leaner, don't we?), but rather that they do so in the absence of significant ill-health effects. Since this is the SuppVersity and not the bb.com bulletin board, I am not going to restrict today's analysis on the health issues. Instead, I will start by looking for scientific evidence that would confirm the common sense assumption that chewing nicotine gums does, in fact, promote weight loss -- in humans, not in rodents (Lupien. 1988). You can find more True or False articles at the SuppVersi...
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Sex, Drugs and... Exercise? Caffeine, Alcohol, Marihuana and Nicotine - Do All Our Favorite Addictions Clash With Being Healthy, Lean and Athletic?

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The only truly ergogenic addiction is a SuppVersity addiction ;-) I am not sure if you remember my detailed elaborations on the effects of sexual intercourse on exercise performance from May 30, 2012 [see "Will Sex Before a Competition Hamper Your Performance?" | more] , but if you don't I'd suggest you start out with this SuppVersity Classic before you devote yourself to Rock'n'Roll by reading up on that in my article "Acoustic Gear" [ read more ] and return here for the missing third part of the triumvirate: Drugs! Drug #1: Caffeine - From your coffee mug to the doping list I am actually 100% confident that 99% of you have already trained "on drugs". Most of you probably do it regularly. Either with caffeine, about which Tony Chou reported in a 1992 paper that it is consumed on a daily basis by ~90% of the adult population (Chou. 1992). With average amounts of "only" 200 mg or 2.4 mg/kg/day (about 2 cups of coffee). ...
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