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There is Such a Thing As Overtraining, Beware! When IGF-1, MyoD & Myogenin Plummet and MAFbx Gnaws Away Your Muscles, It'll Already be Too Late to Acknowledge

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Overtraining is real and it's blocking future and reversing past gains. I am well aware that somewhere out there in the broscientific spheres of the pseudo-experts on the various bulletin boards of a world people call the Internet statements like "there is no overtraining, just undereating" are not uncommon. And in fact, there is a certain connection between the effects / symptoms we usually associate with over training on the one, and the consequences of under eating on the other hand. It's a perfect synergy, if you will - a synergy I have been writing about in the past (suggested read: "The SuppVersity Athletes' Triad Series" | read more ), but it's not what the most recent study from the Sao Paulo State University in Brazil is about (Alves Souza. 2014). Overtraining comes in two forms If this is not your first visit to the SuppVersity the phrases "sympathetic" and "parasympathetic" overtraining will probably sound ...
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The Myostatin Inhibiting & Myogenic Effects of Epicatechin: Cacao & Tea Contain Well-Known But Overlooked Anabolic

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Does a flavanol in " real chocolate" help you shed the fat and build the muscle? If you are like me, you are probably already using cacao to build muscle. Whether the effects of the occasional dark chocolate bar are so profound that you'd notice if you'd skip them, is however questionable. Irrespective of the latest results from Gabriela Gutierrez-Salmean and her colleagues from the University of California , VA San Diego Health Care Systems and the Escuela Superior de Medicina del Instituto Politécnico Nacional at the Seccion de Posgrado in Mexico City present in a soon-to-be-published paper in the The Journal of Nutritional Biochemistry (Gutierrez-Salmean. 2013), by the way. "Epi" as in "Epistane" (*) was yesterday... ... "epi" as in chocolate epicatechin is the future (* Epistane was the brand name of a "pro-steroid"). This could be the take home message of future follow up studies in human beings, if the r...
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The Intracrine Effects of Anabolic Steroids - Metanolone Promotes Stretch-Induced Intramuscular MGF Expression

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Arnold's workout regimen are known to generate a hell lot of wear and tear and actually this could be part of his success formula. I have to admit that the increase in intra-cellular MGF production is probably not the only, but certainly a new and very important pathway by which anabolic steroids "actively" promote muscle growth. According to a recent study from the Department of Rehabilitation and Physical Medicine, Graduate School of Medical and Dental Sciences at the Kagoshima University in Japan (Ikeda. 2013) anabolic agents such as metenolone which is a naturally occuring, WADA-listed long-acting anabolic steroid with weak androgenic (testosterone or androsterone-like) properties. It is isolated from the glands of pregnant domesticated felines, and is supplied as the acetate ester for oral administration and as the enanthate ester for intramuscular injection. Adult doses for the treatment of aplastic anemia are usually in a range of 1–3 mg/kg per day ( Wikiped...
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When Rodents Squat, Scientists Gain Insights into How Muscles Grow. IGF-1 Response to Exercise Does Matter - Locally, not Systemically, of Course!

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You want to build big wheels? Look no further get yourself the "Squat T-Bar" with integrated 15mA electrical 'motivator' (Aguiar. 2012) "A rodent study investigating strength workouts?" Yeah, I know it does not sound like that would be in any ways news-worthy, but if you take a look at the image on the right, you will immediately realize: This study is different! Instead of using a treadmill or simply stitching down (or rather up) one of the hindlimbs of the rodents to induce a chronic overload on the other one (don't laugh, many rodent studies have done just that), the study at hand (Aguiar. 2012), which is going to be published in the next issue of the International Journal of Sports Medicine , used a not innovative, but unfortunately largely forgotten (or overlooked?) torturing device that has been developed by Japanese researchers roughly 20 years a ago (Tamaki. 2012). The rodent torture... ah pardon squat rack ;-) After being fitted with ...
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