Ketone Ester Supplement Boosts Trainees' Post-Exercise Glycogen Repletion by 18% in Insulin-Clamp Study, But...
For the average gymrat, the 18% increase in glycogen repletion PWO is 100% irrelevant and the amounts of glucose you'd need to facilitate it (even w/ ketones) would do more harm than good to your health and physique goals. Who would have thought that? A ketone ester drink ramps up the already elevated insulin levels you'll see after the post-workout ingestion of a bolus of glucose. Probably everyone who doesn't vilify insulin and believes blindly in the label claims of supplement producers. After all, D-β-hydroxybutyrate has long been known to promote insulin secretion in animals - two decades ago Laughlin et al. were among the first to realize their insulinogenic prowess (Lauglin 1994). Even before Laughlin et al. researchers suspected that the ketone-body-induced increases in insulin will go hand in hand with a significant increase in glycogen synthesis as it has been observed in vitro 40 years ago by Maizels et al (1977). What would be news, though, is the fact ...