Antihistamines Block Gene Response to Exercise + Impair its Insulin-Sensitizing, Energizing & Hypotensive Effects
Is all the exercise you do for nothing if you have to take antihistamines? Unlikely, but what appears to be certain is that they have indeed negative effects on the exercise-induced adaptation process that triggers not just increases in insulin sensitivity, but also improvements in blood pressure and mental energy. "An antihistamine is a type of pharmaceutical drug that opposes the activity of histamine receptors in the body," that's what Wikipedia knows about antihistamines. This, and the fact that there are H1-antihistamines and H2-antihistamines, that they target the histamine H1/2-receptors and that they are used to treat "problems" from allergic reactions in the nose (e.g., itching, runny nose, and sneezing) to insomnia... quite the range ;) What Wikipedia does not know, however, is that histamine is "important substance contributing to the normal day-to-day response to exercise in humans" (Romero. 2016a) and that blocking it will also blo...