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Zinc + Multimineral Supplement May Improve Glycemic Control & Lipid Levels in Adult Diabetics

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Diabetes and Pre-Diabetes are omnipresent in today's food-abundance. Healthy, wholesome and nutrient dense foods, on the other hand are either rare or people are just too lazy to obtain them. Thus, it is no wonder that researchers found that mineral supplementation will benefit people with onset or full-blown diabetes. Table 1: Nutrient composition of the preparation for the MVM/Z group ( Gunasekara. 2011 ) In their study, Gunasekara et al. ( Gunasekara. 2011 ) investigated the effect of 4 months of either oral multivitamin/mineral plus zinc sulfate (22 mg/day) (MVM/Z, cf. Table 1) or multivitamin/mineral supplementation alone on blood glucose (fasting and postprandial) and glycosylated hemoglobin (Hb A1C %) and serum levels of zinc , creatinine , and lipids . The zinc+MVM group had a mean change of fasting blood sugar -0.33 mmol/L (standard error of the mean 0.21 mmol/L) and was significant ( P = 0.05) when compared with the other two groups (mean change in the MVM gro...
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GlycoCarn Alone Beats the TOP PreWorkout-Matrices by Lengths

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Primordial Perfomance , among others, has been selling GlycoCarn (R), i.e. Glycine Propionyl-L-Carnitine, for some time now. Recently, Bloomer et.al. ( Bloomer, 2010 ) published a study on the effects of 1 6 grams of maltodextrin (Placebo) or 16 grams of maltodextrin + 4.5 grams of GlycoCarn ® (GPLC) , as well as three different commercially available pre-workout formulas (supplement 1 = Gaspari Nutrition SuperPump 250 , 2 = BSN NO XPLODE , 3 = MuscleTech NanoVapor ) on exercise performance and related blood parameters. The results (cf. table, below) are impressive, except from the bench press performance, where Gaspari Nutrition's SuperPump 250 won the race, nothing beat the 4.5g of GlycoCarn: Exercise performance data of 19 resistance trained men receiving placebo or supplement in a cross-over design. (best values marked by author, Bloomer. 2010 . Table 3) Although the scientists did not provide us with the names of the respective products (supplements 1-3), it was ...
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Beta-Alanine vs. L-Taurine: Study Establishes Inverse Relationship

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Image 1: Beta alanine It is not new that there exists an antagonistic relationship between muscle carnosine (M-Carn, which is increased via beta-alanine supplementation), on the one hand, and muscle taurine (M-Tau) levels on the other.  The study by Harris, et.al. (Harris. 2010) is however the first to report on the immediate effect of supplementing with 2x800mg of a time-released beta-alanine (structure, cf. image 1 on the right. HMDB v2.5 ) formula on muscle taurine content in seven male subjects after four weeks of daily supplementation. A realistic scenario as these dosages can be found both in stand-alone, as well as an kitchen-sink approach supplements such as NO-Xplode & Co : Pre and post supplementation M-Carn was 25.9 ± 4.3 and 41.3 ± 5.5 mmol.kg -1 dry muscle and M-Tau 28.1 ± 7.1 and 22.6 ± 7.0 mmol.kg -1 dry muscle . Despite the 20% fall in M-Tau , values of M-Tau remained within the normal physiological range . Before supplementation M-Tau was negative...
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Glutamine: Alanyl-Glutamine or L-Alanine + L-Glutamine - Is There a Difference?

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Some athletes, mostly bodybuilders, swear by it, yet the results of studies on the ergogenic effect of l-glutamine supplementation are quite unequivocal. A recent study ( Petry. 2010 ) investigated the effect of alanyl-glutamine (DIP, at 1.5 g/kg, n=8) , L-glutamine + L-alanine (GLN+ALA, at 1 and 0.61 g/kg, respectively; n=8 ) or water (CONTR, n=8 ) supplementation on various exercise-related parameters in rats after 21 days of training. The results are promising, yet far from earth-shattering: "Supplementation with DIP or GLN+ALA increased plasma glutamine concentration by 23% and 21% respectively , as compared to CONTR group (p<0.0001). Plasma ammonia concentration was lower in both supplemented groups (DIP, 3.8 ± 0.1 μM and GLN+ALA, 4.1 ± 0.2 μM), compared with CONTR group (5.3 ± 0.2 μM) (p<0.0001). DIP and GLN+ALA groups exhibited in the soleus muscle high glutamine (33.4% and 28%), glutamate (21.7% and 10.8%) and glutathione (GSH, 52.2% and 48.4%), compar...
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Juice Plus does not Prevent Common Colds, but Shortens Phases With Severe Symptoms

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If you are like me, you probably like very concrete studies. Studies such as the one published by Roll et al. in the British Journal of Nutrition ( Roll. 2011 ). In a randomised, double-blind, placebo-controlled trial, the scientists investigated the effect of 4 capsules of Juice+ on healthcare professionals (mainly nursing staff aged 18–65 years) from a university hospital in Berlin, Germany. The results are not earth-shattering, but interesting nonetheless. While supplementation did not decrease the mean number of days the subjects experienced "common cold symptoms", it did decrease the number of days with "severe" symptoms. The scientists summarize their results as follows: Intake of a dietary supplement from fruits and vegetables was associated with a 20 % reduction of moderate or severe common cold symptom days in healthcare professionals particularly exposed to patient contact. Whether you think this is worth the extra bucks for supplements you would not...
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