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Blocking Inflammation is Like Choking the Fire: Long Term Weight-, Visceral- and Android-Fat Gain in Human Study Emphasizes Essential Role of TNF-α in Metabolic Control

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Can cooling down the inflammation make your belly grow!? (Mito-)Hormesis and the important and beneficial role of "inflammatory" cytokines, molecules etc. are one of my favorite topics. It's simply intriguing that health, performance and longevity apparently depend on the presence of a healthy amount (whatever that may be) of inflammation. Even the provision of low dose arsenic does not - as you may expect - shorten, but prolong the lifespan of several common model organisms (Schmeisser. 2013). Findings like these don't just conflict with common sense, they are also in opposition to the still prominent free radical theory of aging and it's central message: Oxidation and inflammation are bad for you! No matter what!  Too little is just as bad as too much Most of you will remember one of my previous articles on (mito-)hormesis - if if that's not the case, I'd recommend you start with the "Inflammation is a True Fat Burner" article ( re...
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