DHT Safer Than Previously Thought: High Blood DHT does not Induce Prostate Cancer
Regular visitors of the SuppVersity will know that the stigmatization of DHT goes without reasonable and conclusive scientific research. In their editorial to the Annals of Internal Medicine Swerloff & Wang ( Swerloff. 2010 ) conclude from the results of more recent studies into the various effects of DHT on different tissues: In normal men, serum DHT levels are approximately 10% of the serum testosterone levels, whereas intraprostatic DHT levels are much higher than serum levels, with the intraprostatic DHT–testosterone ratio being 7 to 8 (12). Although the authors did not measure DHT levels in the prostate after DHT administration , Page and coworkers (13) recently reported that prostatic DHT levels did not increase when pharmacologic doses of DHT were administered (Page S. Personal communication.). These findings are consistent with those of Marks and colleagues (12), which demonstrated that administration of testosterone to mildly testosterone-deficient men increased serum t...