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TMAO: Eggs, Meats and Your Cardio-Metabolic Health | You Can Sill Eat Eggs & Meat, If You Got 'the Right Gut Bugs'

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The (ill) health effects of choline and its pre-cursor l-carnitine in animal products like eggs or (red) meats are probably mediated by a diet devoid of prebiotics... however, simply pounding more resistant starches, for example, seems to do more harm than good. If you have been following the SuppVersity  News on Facebook ( a must , btw ;-)), you will be aware of the "TMAO"-issue. If not, here's the gist: The ingestion of certain dietary nutrients - primarily choline, phosphatidylcholine, and its precursor l-carnitine can serve as a precursor for the ultimate generation of an atherogenic metabolite, trimethylamine N-oxide (TMAO). TMAO, in turn, has been linked to all sorts of diseases, most prominently cardiovascular disease and the formation of atherosclerotic plaque. Unlike "fish odor disease", the choline/CVD link is unrelated to  your genes : DNA-Fit: Train Acc. to 'ur Genes Is Laziness Built Into 'ur Genes? Keep Muscle While Dieting...
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α-GPC and Low Thyroid? Fat Loss+Muscle Gains, Possible? More Protein in Shift-Work Diet, 7kg Lower Fat Mass & TC?

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In today's installment: Alpha-GCP and reduces thyroid function; accurate body fat measurement in contest prep confirms recomp effect; more protein keeps shift workers lean and healthy. Since I didn't want to bore those of you who are (for whatever reason) not interested in significantly annotated summaries of the studies presented at the last ISSN conference, I've deliberately taken a break before publishing the next installment of the #ISSN17 series ; with this one answering important questions such as: Can alpha-GPC supplements give me hypothyroidism? Can lean individuals still do a "recomp", i.e. lose significant amounts of fat while gaining muscle in short periods of time - What does a gold-standard measurement w/ the 4-C method say? And, last but not least, is a higher protein intake the landmark feature of those night shift workers who don't get obese and sick and how does it work? Interested? Alright, here we go... Fasting  and alpha-GPC have sth...
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TeaCrine®, Tribulus, Cordyceps, ALA, Sesamin, Fish Oil & More - The Latest Supplement Science (November 2016)

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Many currently available supplements lack sufficient scientific backup. It has been a while since I published the last supplement science update - the recent release of the latest edition of the  Journal of Dietary Supplements reminded me of that. In issue 1 of volume 14 of this journal that "addresses important issues that meet a broad range of interests from researchers, regulators, marketers, educators, and healthcare professionals" (Aims & Scope according to the publisher ) you will find studies on (you already know that from the headline) "TeaCrine®, Tribulus, Guarana, ALA, Sesamin, Fish Oil & More", studies the design and results of which I will briefly summarize for you in the following paragraphs: Read about rather exercise-related studies at the SuppVersity Tri- or Multi-Set Training for Body Recomp.? Aug '15 Ex.Res. Upd.: Nitrate, Glycogen, and ... Pre-Exhaustion Exhausts Your Growth Potential Full ROM ➯ Full Gains - Form Coun...
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Older Human Study Shows: 2.72g Carnitine per Day Ward Off Fat Gains - Specifically on the Trunk | User Question: Are We Missing Out If We Are Not Using Carnitine?

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SuppVersity reader Derek D. wants to know if 2013 study shows we are missing out if we don't use carnitine. When I answered your questions on Facebook, the other day, Derek D.'s question about the results of a 2013 study by Stephens et al. stood out, because Keller's study suggest that carnitine may be significantly more useful while bulking than it is during a cut (which is still what it is marketed for). If you are a long-term SuppVersity  reader, you will be aware that this is not the first SuppVersity  article discussing a study that points to the use of carnitine outside of dieting scenarios. In 2013, for example, I wrote about a study by Keller et al. (2013). A study that found significant increases in pro-anabolic hormones and proteins, and a 7% improvement in lean-to-total-mass ratio in rodents in response to a relatively low amount of carnitine in the diet. You can learn more about carnitine at the SuppVersity ! Carnitine for Acute Endurance Pe...
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