2.5 mg Nicotine = Ergogenic - 18-21% Increase in Power in Crossover Study | Plus: Are Health or Addiction an Issue?

While cigarettes are neither effective performance enhancers nor safe, nicotine, one of their key ingredients, may be the effective ergogenic aid with a reasonable sides/effects ratio you have been looking for... well, that's at least what the recently published 1st RCT with reliability test and crossover protocol seems to suggest. Yes, nicotine is the main (psycho-)active ingredient in cigarette smoke. It is, however, - and we tend to forget that in the debate about (ab-)using nicotine as a "supplement" - only one out of many "ingredients" of cigarette smoke; ingredients that ruin the health of our lungs and promote the risk of lung and other cancers. It would be haphazard, though, to exonerate nicotine completely, as there is "a direct contribution of nicotine to cancer onset and growth" ( Grando 2017 ). The research on the interaction of individual genetic susceptibility and nicotines ability to activate "nicotinic acetylcholine receptors...