Friday, May 30, 2014

Supplemental NAFLD (Non-Alcoholic Fatty Liver Disease) Protection for Everyone! Regular Alpha Lipoic Acid (300mg) & Vitamin E (700IU) For Less Than $20 Do the Trick!

You don't have to look at the liver of this person to know that he / she is suffering from NAFLD - just like an ever-increasing minority (soon majority) of US citizens
You may asking yourselves what "looking good naked" has to do with obesity and diabetes right now, but if you think about it, the things you have to achieve the one (don't tell me you don't care if you look good naked, liar!) and avoid the others are actually not too different and what's commonly overlooked: The liver is of pivotal importance for both! Looking healthy and being healthy.

In spite of the fact that I am going to get back to the "liver <> diabetes" connection later in the article, I would like to invite you to take a closer look at a previous article on that topic "Liver Enzymes the #1 Marker of Insulin Resistance!? Plus: What Does the Correlation Bettwen HbA1C & ALT, AST and GPT Tell Us About Diabesity?" to catch up!
You can learn more about NAFLD at the SuppVersity

6 Bananas A Day = No Problem For the Liver!

Can We Blame NALFD on Fructose?

Insulin Sensitivity is Determined in the Liver

Saturated Fat & NAFLD - Is there a Link?

Snack Your Way to a Non-Alholic Fatty Liver

No Choline, No Healthy Liver, But Heart Attacks
Now that we are on common grounds in regards to the importance of liver health, it's about time to drop the bomb. Believe it or not, you can help your liver along tremendously with commonly available dietary supplements - and if I am not totally mistaken that will cost you - at most - 20 bucks a month. Certainly not bad in view of the fact that the stack of alpha lipoic acid (regular, not R-ALA) and - you won't believe it - regular vitamin E has just been shown to A
  • CLA always with DHA | learn why
    improve inflammatory cytokine levels, 
  • reduce steatosis scores, 
  • improve homeostasis model assessment scores, and 
  • lower triglyceride levels 
withing only 6 months significantly in comparison to the baseline levels of the to 155(!) patients that were enrolled in the study.

ALA & Vitamin E work - both in conjunction and on their own

In pairs of m=40, the subjects had been randomly allocated to receive either ALA 300 mg, vitamin E 700 IU, or ALA 300 mg plus vitamin E 700 IU, the poor 35 patients who were left were randomized to treatment with placebo.
Figure 1: Changes in selectet parameters of metabolic health over the 6-months study period (Basu. 2014)
As the data in Figure 1 clearly indicates, this was ill fate. Compared to their peers who were treated with alpha lipoic acid and / or vitamin E, they saw significantly less pronounced health improvements in spite of similar lifestyle changes (participants were allowed to consume 1600 calories per day and to participate in moderate exercise, consisting of walking 150 minutes per week at the rate of 100 steps per minute).
No, I would not be scared of vitamin E! If you have NAFLD, there is no doubt that you can benefit from additional antioxidants. Things may look different, for lean athletes like yourself, who tend to fall for the false promises of "nutrient repartitioners" | learn more.
Bottom Line: They are cheap, they can be bought all over the Internet and at every supplement store round the corner and they are effective. Alpha lipoic acid (regular) and vitamin E will boost your efforts to reverse the damage you've inflicted on your liver over the past couple of years and this will have pronounced effects on your overall metabolic health, your lipid and glucose metabolism, your heart disease and cancer risk ("Liver Cancer Kills US Citizens" | learn more) and - of course - the way you look and feel. Not too bad for 100% sage supplements that are worth less than $20 per months, right? Just make sure you don't overdo it. If 300mg + 700IU work, this does not mean that 1,200mg + 2400IU will work better ;-)
  • Basu, Patrick P., et al. "Effect of Vitamin E and Alpha Lipoic Acid in Nonalcoholic Fatty Liver Disease: A Randomized, Placebo-Controlled, Open-Label, Prospective Clinical Trial (VAIN Trial)." Open Journal of Gastroenterology 4.05 (2014): 199.