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Albuterol / Salbutamol Doping Works! Cyclists Just Have to Take One Pill For a 4.1% Increase in Peak Power. Plus: Its Chronic (Ab)Use Makes Their Training More Efficient

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Inhaling salbutamol, which is the most appropriate way to combat asthma, will not provide the same beneficial effects to athletes as taking a much higher doses pill and thus "going systemic" will (Norris. 1996; Koch. 2013) Salbutamol (INN) or "albuterol", as it is called in the US, is a short-acting β2-adrenergic receptor agonist. Just like its longer-acting brother clenbuterol, it has been developed to be used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease; and just like its brother clenbuterol, it has been and still is abused by athletes all around the world as a doping agent. For good reasons? Well, a recent study from the University of Copenhagen would suggest just that. After all, the scientists from the Department of Nutrition, Exercise & Sports , Section of Integrated Physiology found acute and long(er) term beneficial effects of salbutamol (ab)use on peak power in their subjects, 20 male endur...
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Eight Weeks on Moderate Doses of Erythropoietin (EPO) Build a Bigger Mitochondrial Engine and Shed Some Body Fat, but is That Really Worth Taking the Risk?

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Image 1: These EPO containing Recormon vials are highly popular in the French Pyrenees ;-) Fatty acid oxidation is certainly one of the buzzwords in the supplement industry. Interestingly enough, it is mostly used very indiscriminately for all sorts of physiological processes which are sometime more, sometimes less related to the actual process of β-oxidation, in the course of which the acetyl CoA are liberated from their original molecular bond. In fact, the majority of the currently available "fat burners" (those neat little pills with tons of fat liberating, but not burning stimulants in them) has no effect on the efficacy of this process. In previous posts, as the one on irisin and the utility of exercise induced increases of PGC1-alpha ,  I have already hinted at the importance of "building a bigger engine", or, more formally, increasing the oxidative capacity of your mitochondria in your individual battle against your love handles and the global battle a...
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