Vitamin D Levels Associated with Adipose Fat Mass

Today is the day for our weekly news on vitamin D (never hard to find some ;-) Sciencists from Atlanta (Lin. 2010) recently found that the dramatic weight loss patients experience after roux-en-y gastric bypass (RYGB) surgery goes hand in hand with an initial increase in plasma 25(OH)D concentration:
Strong positive baseline and 1 month cross-sectional correlations between FAT and plasma 25(OH)D were observed, which remained after adjustment for age and race subgroup (β = 0.76 and 0.61, respectively, P = 0.02)
Interestingly, this intermittent increase was followed by a decreasing trend over the rest of the 24 month study period, so that
Despite temporary improvement in vitamin D status, a high prevalence of vitamin D insufficiency was observed (76, 71, 67, and 82%, at baseline, 1, 6, and 24 months, respectively), and plasma 25(OH)D concentrations were lower in AA compared to white patients (P < 0.05).
The scientists conclude that in the course of the dramatic weight loss of the first weeks after surgery stored vitamin D was released from the fat cells and thus contributed to the temporary increase in vitamin D levels. This, however, was not enough to restore 25(OH)D levels, which tend to be depressed in obese individuals, anyway, to the normal range. Supplementation may thus be warranted.
Disclaimer:The information provided on this website is for informational purposes only. It is by no means intended as professional medical advice. Do not use any of the agents or freely available dietary supplements mentioned on this website without further consultation with your medical practitioner.