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Olive Leave Extract Equally Effective at Lowering Blood Pressure as ACE Inhibitor Captopril

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For those who read yesterday's news on the negative effect of caffeine on exercise induced blood pressure response, it might be of interest that no more than 500mg of Olive ( Olea europaea ) leaf extract may well counteract the negative effect of caffeine intake and help with triglyceride levels, as well. In a double-blind, randomized, parallel and active-controlled clinical study ( Susalit. 2010 ) an international team of scientists found that after a run-in period of 4 weeks continued subsequently by an 8-week treatment period supplementation with Olive ( Olea europaea L. ) leaf extract (EFLA®943) at 500 mg twice daily was equally effective in reducing blood pressure as the ACE inhibitor Captopril , which was given at the dosage regimen of 12.5 mg twice daily for the first two weeks and (if necessary) at 25 mg twice daily for the rest of the treatment period: After 8 weeks of treatment, both groups experienced a significant reduction of systolic blood pressure (SBP) as well ...
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Caffeine Blunts Exercise Induced Hypotensive Response and Increases Post Exercise Blood Pressure

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I told you about the positive effect of caffeine supplementation on the post high intensity interval training fatty acid oxidation, only yesterday. Today, I have to tell you that all that could be a bad idea, if you are prone to hypertension, because, as scientists from Brazil found ( Cazé. 2010 ), the same caffeine that may make you shed some additional grams of fat, will block the hypothensive, i.e. blood pressure lowering effect of exercise and may drive an already high blood pressure into the danger zone: Seven hypertensive subjects (52.3 +/-3.3 years), being 5 women, accomplished two walk sessions with 40 minutes of duration, in two days of training, having previously ingested CA (4 mg/kg of body weight) or placebo (PL). BP and heart rate were verified previously to the ingestion, after 15, 30, 45, 60 minutes of the ingestion, at rest and with 10, 20 and 30 minutes after exercise. [...] BP mean increased from 124.9/80.9 mmHg before ingestion to 129.4/84.3 mmHg 60 minutes later ...
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Nitrate Supplementation Lowers Blood Pressure and Exercise O2 Costs

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The hype around creatine and amino acid nitrates already calmed down. For many costumers (me included) real world results could not keep up with the promises made in glossy adverts. A recent study by Vanhatalo et al. (Vanhatalo. 2010 ) does yet show that nitrate supplementation can in fact influence physical responses to endurance exercise: The exercise protocol (two moderate-intensity step tests followed by a ramp test) was repeated 2.5 hours following first ingestion (0.5 L) and after 5 and 15 days of BR and PL. Plasma [nitrite](Baseline: 454 ± 81 nM) was significantly elevated (+39% at 2.5 h post; +25% at 5 days; +46% at 15 days; P<0.05) and systolic and diastolic blood pressure (baseline: 127 ± 6 and 72 ± 5 mmHg, respectively) were reduced by ~4% throughout the BR supplementation period (P<0.05). Compared to PL, the steady-state O2 during moderate exercise was reduced by ~4% after 2.5 hours and remained similarly reduced after 5 and 15 days of BR (P<0.05). [...] Thes...
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