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You Cannot Sleep Before an Important Event? Take High Dose Creatine or Low Dose Caffeine to Battle Fatigue Induced Decrement in Skill Performance and Increase Testosterone.

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Image 1: LG's Anadraulic State is only one example for some of the 2nd generation pre-workout products with deliberately lowered amounts of caffeine and increased amounts of creatine & other ergogenics in it. You know it, you love it: Creatine Monohydrate - the godfather of dietary supplements ; but did you know that Creatine supplementation at 50 or 100mg/kg body weight is as effective as low (1mg/kg) or high dose (5mg/kg) caffeine in preventing the decrease in athletic skill performance after sleep deprivation? On ten separate occasions, Cook et al. ( Cook. 2011 ) had ten elite rugby players complete 10 trials on a simple rugby passing skill test (20 repeats per trial). On five of these occasions the players had slept their usual 7-9h on the other five occasions, however, they only slept 3-5h before reporting to the laboratory. While the 2-6h of sleep they were lacking "resulted in a significant fall in skill performance accuracy on both the dominant and non-d...

Tinospora Cordifolia as in LG Sciences' Natadrol is a Potent Antioxidant and Metal Chelator

This is only a small news-item, but unfortunately scientific background info on commercially available supplements is pretty rare - so here we go... Scientists from India ( Bhawya. 2010 ) investigated the antioxidant potential of various extracts of Tinospora Cordifolia (the primary ingredient in LG Sciences Test Booster Natadrol ) and found that ... Methanolic, ethanolic and water extracts showed significant antioxidant potential compared to other solvents and also possess metal chelation and reducing power activity . In the DPPH radical scavenging activity, methanolic extract  (98.13%)  showed high antioxidant potency, ethanolic  extract (90.34%) was a potent scavenger of superoxide radical. At the same time, both methanolic (97.08%) and ethanolic extracts  (95.21%)  inhibited hydroxyl radical along with other extracts. The metal chelation  in methanolic  (60.62%), ethanolic  (57.62%),   aqueous extracts  (40.89%)  and r...

LG Natadrol: A Short Write-Up

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A few weeks ago, LG released Natadrol , a product containing a new, self-proclaimed  "potent muscle-building androgen found naturally occurring in our environment". Sounds like an invitation for a "SuppVerSive" investigation into its somewhat exotic ingredients .* So lets see what we have here * Tinospora Cordifolia (TC) has androgenic activity, established exclusively in the prostate ( Kapur. 2009 );  lowers blood sugar ( various studies );  good for immune system ( various studies );  potent antioxidant ( Singh. 2006 );  good for the heart ( Rao. 2005 );  hypolipidemic, i.e. it lowers blood fats ( various studies ) Overall: If TC is androgenic in the prostate it might as well work as an androgen elsewhere, other than that there is no evidence that apart from being "healthy" (outside the prostate) it might in itself be anabolic . Note: LG is honest and lists it under "androgenic factor" < so their claim holds true, yet it has...
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