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Leucine Inhibits Nitric Oxide & Beneficial Effects of Cardio Training on Glucose Management. Plus: No Increase in Protein Synthesis W/ Protein After Eccentric Workouts?

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Pre-, Post and Intra-workout supplements are a multi-million dollar business. But are the products at least half as effective as the shiny advertisements claim? Let me guess, the actual reason you want to read this article is the shocking claim that everybody's darling, the "pro-anabolic amino acid" leucine may, in addition to having beneficial effects on the phosphorylation of mTOR and the subsequent increase in skeletal muscle protein synthesis, also have negative effects. Right? Ok, I will add a link that takes you right to my elaborations on two recent studies from the São Paulo University and the China Agricultural University and allows you to skip past the information about another recent study. A study from the Department of Public Health at the Aarhus University and a study that raises the question, whether its results are indicate that eccentric training is potent enough to maximize the protein anabolic response to an extend that the additional provisio...

Study Says "BCCAs, Don't Build Muscle!" I Say "True, But They Seem to Create an Anabolic Potential." Plus: Potential ≠ Growth ➲ You're Still Better Off With Complete Protein

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The above is a question way too many trainees ask: "Who the f*** needs BCAA supplements?" Ok, the industry, but who else does? They are not sold as the "next best thing", they are sold as "the best thing" any ambitious trainee may be taking. As a regular, here at the SuppVersity , you will yet know that despite all their advantages , the BCAAs, leucine, iso-leucine and valine, also have their downsides ("The Neurotransmitter Depleting Effects of Branched Chain Amino Acids (BCAAs) and Their Potential Ergolytic, Anxiogenic & Depressive Downstream Effects" | read more ) and should not be all too surprised by the "news" that "BCAAs don't build muscle". A news I gathered from a study by scientist from the Wayne , the Northeastern , the Victoria and the Texas A&M Universities ; a study that says that the provision of 120mg/kg body weight of BCAAs did not augment the protein synthetic effect of resistance trainin...

22g High EAA (6g) Protein + 36g CHO Pre- / Intra-Workout Boost Fat Oxidation & PWO Resting(!) Energy Expenditure

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I don't doubt that you can do that, too! It does sound awkward: If you mix Twinlab: Amino Fuel (22 g protein - 6 g essential amino acids | L-phenylalanine: 633 mg; Lvaline: 781 mg; L-tryptophan: 133 mg; L-threonine: 679 mg; L-isoleucine: 565 mg; L-methionine: 292 mg, L-histidine: 282 mg; L-leucine: 1350 mg; L-lysine: 1449 mg) with a regular  sports recovery drink that contains 36g of simple sugar, down half of the resulting 800ml serving of whatever you want to call this mix immediately before your workout and consume the rest during the rest periods between sets, this will have measurable effects on your resting energy expenditure and fat oxidation. From long-term to short time effects At first, it does questionably sound counter-intuitive that the ingestion of an EAA + carbohydrate mixture before / during would increase the resting energy expenditure and rate of fatty acid oxidation after your workout. On the other hand, if you think about the long-term effects of co...

Creatine Before or After the Workout? Finally the Answer is Here! Study Says: Better Take it After for Mass & Strength

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The old "creatine = water retention" myth is - at least for the majority of athletes - just that: a myth and a result of the old practice of "loading" with copious amounts of creatine and even more high GI carbs. And it is certainly not a problem that's specific to cheap and effective creatine monohydrate. In case someone of you ever asked me, whether he or she should take his or her creatine before or after a workout I will probably have answered something like: "I don't think it will make much of a difference, but I personally would suggest you split the dosage". Now that Jose Antonio and Victoria Ciccone (the first of whom many will probably know from his old radio show on BB.com, the countless articles he wrote, his job as an editor or whatever else), published a paper in the Journal of the International Society of Sports Nutrition , it appears my new answer to the said question would be: "It looks like it's better to take your c...

Peri-Workout Hydro-Whey Supplementation: Tried & Proven Muscle Builder Will Also Increase Tendon Size & Strength

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Squats are by no means the only exercise that requires strong muscles and tendons. In a way you could argue that today's SuppVersity article serves two purposes. Firstly, it provides direct evidence for my outrageous claim that the VPX Shotgun + Synthesize study from Saturday's installment of On Short Notice has little to no practical value, because the use of 2x17g of maltodextrin as a control has little to do with the real-world supplementation regimen the potential consumers of respective products are ingesting. I mean, you can safely assume that people who are willing to spend the money on expensive peri-workout kitchen sink supplements will - just like most of you - be ingesting a whey (or other fast acting) protein source after their workouts, anyways. It goes without saying that it would not have needed a new study to prove this point, so that informing you about another observation Farup et al. made in their most recent study is not just the second, but actually...

Cod Liver Oil vs. URTI. 2x Higher Fat Oxidation W/ Optimal Workout Timing, Aggressive Diabesity Control, Seaweed & Breast Cancer and NO Supplements Superior to Sugar

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Self-proclaimed experts will say: "No cod liver! It's poison! It has way too much vitamin A... you better pop a kg of vitamin D pills if you want to do something for your health." Really? How do you explain the results of the Robertson study, then? "Grandma was right" - That's if you will the statement of the week - a statement that is verified by the SuppVersity Figure of the Week which is p = 0.04 and describes the probability that the association between the consumption of cod liver oil and a decreased occurrence of upper respiratory tract infects (URTI) Swedish researchers observed in a cohort of 6350 middle-aged and elderly participants in the Tromsø Study 6 , of which Robertsen et al. had actually expected that it would finally confirm the protective effects of high(er) vitamin D levels / intake against respiratory disease. As it turned out, however, neither vitamin D (25-OHD), nor the intake of fish, n-3 capsules or vitamin and/or mineral suppl...

Triphasic Nutrient Supplement W/ Caffeine, Aminos, Carbs, Creatine & All the Usual Suspects Allows For Higher Training Volume, Lowers Cortisol & Dampens Muscle Damage

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Do you really need the whole pre-, intra-, post workout supp-arsenal to benefit from your workouts? Finally, another workout supplementation study! Yeah, I know you are already suffering the side-effects of withdrawl, but it's just a couple of lines and you will feel relieve - thanks to Stephen P. Bird and his colleagues from the Charles Sturt University in Bathurst, Australia, whose latest paper is about to be published in one of the upcoming issues of Nutrition Research (Bird. 2013). And as if that was not already enough, the participants were strength trained athletes , the  physical activity and diet were standardized according to pre-recorded habits and the supplementation protocol was extensive ! With pre-, intra- and post-workout supplements it was exactly what many people today seem to believe was necessary to see any gains ... but is that true? Do you really need all that stuff? The Australian researchers probably had a similar question in their minds, when th...
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