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High Dose Caffeine Restores Insulin Sensitivity and Limits Total as Well as Visceral Fat Gain Due to High Sugar Diets

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Yes, the study at hand is on caffeine, but the results are relevant for coffee, too. A decade ago, the medical community though coffee would dehydrate you, would make you insulin resistant and would increase your risk of heart disease. Recent studies show that coffee does not negatively affect your hydration status (Killer. 2014), that higher coffee consumption is associated with reduced diabetes risk and increasing your coffee consumption can reduce your risk of T2DM (Akash. 2014) and that a "daily intake of ∼2 to 3 cups of coffee appears to be safe and is associated with neutral to beneficial effects" on coronary heart disease, congestive heart failure, arrhythmias, and stroke (O'Keefe. 2013). Against that background it may not be as surprising as it would have been 10 years ago that Joana C. Coelho, et al. (2016) found caffeine to be able to restores insulin sensitivity and glucose tolerance in high-sucrose diet rats. And yet, I personally believe that it is stil...

What's Worse for Your Body Composition & Liver Health? 10g of Sugar from Coke or the Same 10g From Cookies? Plus: Liquid Sucrose is Harder on the Liver Than Fructose

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Hard do believe, but the 10g from coke may actually do more harm than the same amount from cookies. If you want to scare me away from a discussion about the "fat problems" the US and large parts of Europe are struggling with, you just have to repeat Taubs'ian statements such as "if we had not eaten carbohydrates all the mess wouldn't have happened." It's certainly true that the exorbitant and mislead carbohydrate intake and the psyochological consequences ("Fat is bad, isn't it?") of the "low fat" decades from the 1970-1990s is part of the problem, but when we look closer, it's not as simple as to say "we don't eat enough fat". As Yvonne Ritze and her colleagues from the University of Hohenheim , the Technische Universität München , and the Interdisciplinary Obesity Center in Rorschach (Switzerland) write in their latest paper in PLoS One , it's rather the unhealthy conglomerate of "changes in ...

Fructose-Nation: No Change in Fructose Availability in the US Since the Early 1970s. So Why Are We Fat, Then?

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From fat to Fructose - just another scapegoat for a fundamental problem? Over the past 5 years or so, the idea that that fructose is to blame for the ever-increasing rates of diabesity has become so popular that hypotheses such as "the fructose consumption has exploded over the past decade" are usually accepted as scientifically verified facts. A recent paper from the Department of Nutrition and Health Sciences at the University of Nebraska did now remind me that not all things that appear logical and consistent with our believes are necessarily true. Do we even consume that much fructose? As Trevor J Carden and Timothy P Carr point out, "the consumption pattern of fructose and other key nutrients" in the past 4 decades, "remains a topic of debate" (Carden. 2013). To determine whether fructose consumption in the US has increased sufficiently to be a casual factor in the rise in obesity prevalence Carden and Carr analyzed the USDA Loss-Adjuste...

Sugar Sweetened Beverages, Bottled Water & the Obesity Epidemic: Evidence, Counter-Evidence & Scapegoatism

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SSBs worse than an obesity pill? It is a given fact that neither I nor any sane researcher is going to debate the over-consumption of sugar sweetened beverages are part of the reason s why we are fat. The way they are currently portrayed as the worst invention since trans fats, could however fire back on us. You do just have to look how willingly the oil refiners are bashing the corn refiners, how the fruit "juice" industry claims that their "healthy 100% fruit juices were less obesogenic" than a coke (which is clearly not the case) and how consumers are standing in the line at their local fast-food outlet thinking about taking the diet coke with their menu to be able to have an additional "healthy fruit smoothie" as a dessert. I had all that in the back of my head already, when I hit on a related "Pro v Con Debate" in the early views (articles that are not yet available in the print edition) of the Obesity Reviews and thought that you ...

Sugar Addicted or Just Stressed Out? Study Investigates Modulatory Effects of Different Macronutrient Compositions on Serotonin in the Presence and Absence of Stress

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Image 1: She has the reason she is so relaxed right in her hand... but does she know that sugar is no sustainable way of coping with stress unless you don't care that you thusly pave the way from from initial episodes of hypoglycemia over binges, to obesity and diabetes. "Sugar addiction" is a recurring theme in the blogosphere and whether it exists or not and what potential causes and treatments might be is still a matter of a partly very emotional debate. If we go by the definition of "addiction", of which the venerable Oxford English Dictionary says that it was "a condition characterized by regular or poorly controlled use of a psychoactive substance despite adverse physical, psychological, or social consequences , often with the development of physiological tolerance and withdrawal symptoms", it would be, if we had prove that sugar is a "psychoactive" substance. After all, the "adverse physical, psychological, or social consequ...

Glucose Intolerance in Obese Rats Due to High Carb Not High Fat Diet

While common wisdom tells us that a high carbohydrate + high fat diet will make us fat and sick. A new study by Fleur et al. ( Fleur. 2010 ) indicates that a free-choice high-fat high-sugar diet induces glucose intolerance in absence of obesity. Also, rats fed a high-fat (low carb) diet avoided the negative effects on insulin tolerance despite similar comparable body weight gains: Interestingly, the HF [=high fat] diet did not affect glucose metabolism , whereas the HFHS [=high fat, high sugar] diet resulted in hyperglycemia, hyperinsulinemia and in glucose intolerance because of a diminished insulin response. The researchers conclude... these results suggest that not only obesity or total caloric intake, but the diet content also is crucial for the glucose intolerance that we observed in rats on the HFHS diet. This is just another of a handful of studies published in the course of the last months which argue against the high-fat = diabetes theory, many people (including pra...
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