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Your Meat Consumption is Probably Not the Reason You're a Creatine Non-Responder: 5% Faster 50m-Sprint Time in 6 Days W/ 20g/day of Creatine for Vegetarians & Omnivores

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It's hard to be a non-responder andno way to change it. In some people the ingestion of creatine appears to be ineffective. Aside from minor diarrhea, when they increase the dosage to the 20g+ range per day in a desperate effort to reap the benefits of one of the, if not the only tried and proven natural ergogenic with significant (real world!) effects, these creatine non-responders don't get any results from either creatine monohydrate or any of the fancier, but mostly inferior "advanced creatines" you can buy at you local, national and international supplement vendor. One of the commonest and eventually most reasonable explanation for "non-responding", I've heard is the hypothesis that non-responders have a high enough creatine intake from meat that would reduce any additional benefit from supplemental creatine to unmeasurable levels. You can learn more about creatine at the SuppVersity Creatine Doubles 'Ur GainZ! Creatine, DHT ...
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CoQ10 for Ultra-Endurance Athletes: 150mg of Ubiquinone Reduce Stress & Inflammation and Stabilize Cell Membranes in 52.4 Mile Torture from 640m to 3,393m!

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Image 1: Susan Kokesh, blogger and the Crazy Running Mum at the Sierra Nevada ultra-endurance run a 52.4 miles "double marathon"   in September 2010; I probably would not even have survived this torture - respect! As a health conscious physcial culturist, you are probably aware that the vitaminesque nutrient CoQ10, which, due to its ubiquitous presence in all living beings, is also known as ubiqinone , plays a fundamental role in cellular bioenergetics . It is a necessary cofactor in the mitochondrial electron transport chain (i.e. your cell's way of "breathing", its respiratory chain) and is therefore essential for the production of ATP, the fundamental energy unit your cells are operating on. In that, CoQ10 works as a mobile redox agent that shuttles electrons and, interestingly, also protons (those little blue and red balls from Bohr's atom model ;-) in the electron transport chain. Within the health and fitness community, it is however better known...
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Ask Dr. Andro: The Pharmacokinetics of Creatine (Part I/II) - How Is Creatine Absorbed into the Bloodstream?

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Illustration 1: There is a bunch of things that could potentially go wrong with creatine uptake: The creatine from dietary sources could be mal-absorbed (1) in the small intestine, (2) not make it into the cell, or (3) be excreted too readily either before or immediately after it was transported into the muscle. Question from Lerner (via comments): Do Creatine Transporters behave the same as glucose transporters? (I.e., serum insulin binds to cellular insulin receptors, which causes Transporters to migrate from inside the cell to the plasma membrane - and the Transporters then pull in the external glucose.) Answer Dr. Andro: As you may have noticed, I took the freedom to set Learner's question into a broader context. A context I broached in my dissertations on Athletic Edge Nutrition's new creatine product Creatine RT on Tuesday, Aug 16, 2011. Thus, the questions I will be trying to answer (unfortunately, I have to rely on existing studies and do not have my...
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Victorious Veteran: Creatine Monohydrate Still First Class! Usefulness & Safety of “Innovative” Creatine Formulas Questionable.

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If we discount a high protein intake as a regular constituent of a healthy diet, creatine is unquestionable the King of Natural Ergogenics. Its impact on athletics way beyond the Gold’s Gyms of the bodybuilding world is evident from its being cited as “effective and safe” in almost each and every “position stand” published in one of the journals of the various sports & nutritional societies all over the world in regular intervals. Thus, with the (nephro-)toxity myth being finally dispelled, creatine has become a stable in the supplement regimen of both recreational, as well as professional athletes. Now, the financial revenue you can make from a non-patentable amino acid that is commonly found in fish and meat products is obviously limited . Thus, the steadily increasing number of players on the supplement market is continuously trying to “reinvent the wheel”, by putting forward a new, better-absorbed, more effect, side-effect free or whatever else the marketing guys had on the...
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Creatine Safe! For Diabetics, as Well.

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Ever since creatine has been introduced to the supplement market there is a certain part of the medical establishment who condemns every body builder's favorite supplement as kidney killer no1 . While there have been numerous studies that showed that healthy people are not at risk of kidney problems or even kidney failure from creatine consumption the study by Gualano et al. (Gualano. 2010) is the first to show that even type 2 diabetics can safely consume creatine: The creatine group presented higher muscle phosphorylcreatine content when compared to placebo group (CR Pre 44 ± 10, Post 70 ± 18 mmol/kg/wt; PL Pre 52 ± 13, Post 46 ± 13 mmol/kg/wt; p = 0.03; estimated difference between means 23.6; 95% confidence interval 1.42-45.8). No significant differences were observed for (51)Cr-EDTA clearance (CR Pre 90.4 ± 16.9, Post 96.1 ± 15.0 mL/min/1.73 m(2); PL Pre 97.9 ± 21.6, Post ...
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