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Anti-Microbial Effects of Artificial Sweeteners in Humans - 2/3rds of a Can of Diet Coke May Have a Sign. Effect on the Gut Microbiome, but the Relevance is Questionable

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2/3 of this can may suffice to make a difference. Whether this difference is (a) relevant or (b) irrelevant is yet as questionable as whether the changes the scientists observed will (i) have a negative (ii) a positive or (iii) no effect. As a SuppVersity  user you know that the whole craze about aspartam and sucralose is overblown. You will also know that any potential "pro-insulinogenic" effects occurred only in less than a handful of human studies. If they did, though, they occurred in response to the ingestion of artificial sweeteners and  glucose or other insulinogenic carbohydrate sources ( learn more ). Against that background it's also not surprising that in clinical trials vs. observational bogus, artificial sweeteners have been shown to help people with weight problems lose body fat ( learn more ). The one thing about the myth of the bad sweetener that has yet not been completely debunked, though, revolves around their negative effects on the human gut mic...
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Sweetener Update: Chronic Aspartame & Acesulfam-K Use Doesn't Mess W/ Your Microbiome | No Link Between Bad Lifestyle & Sweetener Use | No Good Advice from Dietitians

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There's no scientific evidence that any of the various forms of "natural" sugar replacements like brown sugar & co would be better than artificial sweeteners. Since artificial sweeteners their (non-existent) impact on insulin and, more recently, their effects of the gut microbiome are recurring topics in the Facebook messages I receive, I thought it may be nice to briefly summarize potentially relevant results of some of the more recent papers which put a questionmark behind some of the commonly heard "anti-sweetener" arguments, ... including the recently voiced objection that they would mess up your microbiome. To this ends, I have conducted a brief database search, the results of which I will summarize briefly in only one to two paragraphs: You can learn more about sweeteners at the SuppVersity Unsatiating Truth About Artif. Sweeteners? Will Artificial Sweeteners Spike Insulin? Sweeteners & the Gut Microbiome Each is Diff. Sweet...
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Not All Artificial Sweeteners Are Created Equal: New Studies on Aspartame, Acesulfame-K & Combination of Saccharin + Neohesperidin Dihydrochalcone

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It was about time for an artificial sweetener update, wasn't it? Alright, I have to admit I am not following the artificial sweetener scene closely enough to have heard about SUCRAM, an artificial sweetener that is composed of saccharin (a classic) and neohepseridin dihydrochalcone, the new kid on the blog, which is yet not officially approved by either the FDA or it European equivalent o be used in the processed junk, most people call "food", these days. If we put some faith into the latest study investigating the effects of this agent, which is apparently already heavily used in animal feeds in Europe it does yet "dramatically reduce enteric disease" and "enhance growth performance in early-weaned piglets." (Daly. 2014) Whether and to which extent these beneficial effects on gut health are mediated by changes in the gut microbiome is yet still uncertain; and since "uncertain" is a word scientists don't like, Kristian Daily and his...
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Sucralose, Hazardous or Innocent? A Review of the Review - Part I: Glucose, Insulin & GLP1 | Sucralose & Diabetes?

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Sweet, low and unhealthy? Is sucralose as bad as a recent review would suggest? I guess I could say "I've written more than enough about artificial sweeteners!" and simply ignore the sensational press release about the "bioactivity" of this increasingly common artificial sweetener you've read on the SuppVersity Facebook News, yesterday ( check it out ). In view of the fact that most of my previous artificial sweetener articles revolved around a possible impact on body weight / insulin sensitivity, ca. 90% of the claims in the press release are actually "news" - even for SuppVersity readers. Ample reason to take another, closer look at the study outcome and analyze both the "real" results, what the press release made of it and whether or not the panic that's already spreading on the Internet is warranted. First things first: What are we talking about? As the press release informs us, an "extensive review published by Taylo...
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Science Round-Up Seconds: The Pro-Insulinogenic Effect of Artificial Sweeteners + Mechanisms & Consequences

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Would having your coffee with splenda instead of sugar make this cookie even more hazardous for your glucose metabolism and what about your waistline? If you've listened to yesterday's installment of the science Round-Up your are probably already in the know of the most important facts about the "pro-insulinogenic" effects of sucralose and how it is (a) neither sure what exactly is causing this increase in post-prandial insulin release, nor (b) whether this is the "bad thing" conventional wisdom would dictate it is. If you've also read the corresponding press release from the Washington University in St. Louis , I've linked in yesterday's Facebook post on the matter, you will know that even the authors of the study are not yet sure about the real world implications of their results: "The elevated insulin response could be a good thing, she pointed out, because it shows the person is able to make enough insulin to deal with spiki...
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The Unsatiating Truth About Aspartame, Acesulfam K, Sucralose & Co: They Don't Induce Glucose or Insulin Spikes, But Do They Make You Hungry?

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Image 1: If you plan to eat the stuff on the plate behind the coffee cup, I guess it does not really matter if you use sugar, fructose, Aspartame, Acesulfam K, Sucralose or everybody's  new darling, stevia to sweeten the coffee ;-) If there was a yearly top 10 list of the furiously and most passionately debated topics, in the health & fitness community, the issue of "artificial sweeteners" (personally I would include high fructose corn syrup as "artificial", but I guess the FDA or rather their financiers think otherwise) would probably make it to the TOP 5 every year. All concerns about toxicity issues aside, the two main concerns people are worrying about are a direct negative effect on glucose metabolism and an indirect intake on subsequent / concurrent food intake . Both would obviously predispose consumers who buy respective products because they trust in the industry's promise that they would help the lose weight and/or ward off diabetes to th...
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