Posts

Showing posts with the label eNOS

Popular topics

Show more

Exercise News Round-Up: The Latest on Weight Lifting, Steady State, HIIT, Pyramid Training & Co, Their Effects on Body Composition, Leptin, Muscle Morphology & More

Written by | published on
Image
Running may be the "original exercise", but there is more to physical culture than that - irrespective of your gender, by the way; HIIT would be one thing, weight lifting the other that must not be missing from your regimen which can yet still benefit from one or another classic cardio session (img womanshealthmag.com). I must admit that I am a bit lazy today and not really in the mood of writing a lengthy post on circadian rhythms . The weather is awesome and I think I'd better spend the time in the sun recharging the batteries of my circadian clock, than sitting in front of a computer screen. Since I do know that the former, i.e. the good weather won't apply to all of you and that reading these posts does not take anywhere as long as writing them, I will yet put together the promised post on "exercise news" - and I can tell you there is half a dozen of them, such as liver health, aerobics and strength training no leg-based cardio on leg day aero...
Read full article »

Epigenetics - From Mother to Child: Retinoid X Receptor-α Methylation "May Explain >25% of the Variance in Childhood Adiposity"

Written by | published on
Image
A few blogposts "ago", I reported the negative influences maternal (over-)nutrition may have on the unborn child . A recent study ( Godfrey. 2011 ) from the University of Southampton provides insights into which detrimental genetic switches underlie a disadvantageous pre-natal metabolic programming, the consequences of which may well be one of the myriad of factors contributing to the global increase in (childhood) obesity. Figure 1: Rise in childhood obesity from 1963-2008 (from CDC.gov ) Godfrey et al. analyzed the methylation status (if a gene is methylated it is turned off) of several genes in the cord blood of newborns from two independent cohorts (cohort 1: 68 samples; cohort 2: 31 samples) and found that [i]n cohort 1, retinoid X receptor-α (RXRA) chr9:136355885+ and endothelial nitric oxide synthase (eNOS) chr7:150315553+ methylation had independent associations with sex-adjusted childhood fat mass (exponentiated regression coefficient [β] 17% per SD change i...
Read full article »

MRI's NO2 Platinum: Useless Arginine Supplement!?

Written by | published on
Regular visitors of the SuppVersity will remember the study on Size On Maximum Performance , which - despite being financed by Gaspari - showed, from an objective perspective, only marginal effects on exercise performance. MRI was not so lucky to sponsor Reid et al. (Reid. 2010) who studied the effect of their pre-workout product, NO2 Platinum exercise induced increases of nitric oxide: From the pre-exercise blood samples at each exercise session, L-argninine decreased 0.89% in the placebo group after supplementation, whereas the NO2 group significantly increased 84.67% (p = 0.001). Brachial artery blood flow was significantly increased in both groups (p = 0.001) immediately post-exercise, but was not different between groups . Nitric oxide was shown to significantly increase in both groups (p = 0.001) immediately post and at 30 min post-exercise, but was not different between groups. eNOS was significantly increased in both groups (p = 0.028) immediately post and at 30 ...
Read full article »
Disclaimer:The information provided on this website is for informational purposes only. It is by no means intended as professional medical advice. Do not use any of the agents or freely available dietary supplements mentioned on this website without further consultation with your medical practitioner.