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Whey or Casein? Which Would be the Better "Staple" Protein Source for Your Trip to Desert Island?

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Image 1: They are both sourced from cow's milk, but which is the better part? Whey, the byproduct of cheese production, or casein the cheese protein, itself? A recent study would suggest that it's the "waste product" you would have to chose if you could only have one. " Whey is the way to go! " I suppose even I have had a headline like that in one or even several of the daily news items, here at the SuppVersity - and rightly, so! With it's high content of branched-chain amino acids (BCAAs) this fast-digesting protein source is certainly the #1 choice for anyone whose goal is to build lean muscle tissue . Whey's slow-digesting brother casein, on the other hand, is often hailed as the "muscle-preservative", the 24h-protein source that will prevent muscle catabolism, when for whatever outrageous reason (like sleep, for example) you cannot ingest your bi-hourly protein shake... well, I guess those of you who have been following the Intermi...

An In-Depth Look at How You Get Fat: You Acquire More Rather than Bigger Fat Cells

Scientists from the National Institute of Health in Bethesda, Maryland ( Jo. 2010 ) have investigated the exact cellular pathways of weight or rather fat gain. They report: We found a qualitatively universal adipose tissue remodeling process in all four fat depots: 1), There is continuous recruitment of new cells under weight gain; 2), the growth and shrinkage of larger cells (diameter >50 μm) is proportional to cell surface area; and 3), cell loss occurs under prolonged weight gain, with larger cells more susceptible. It needs some interpretation of the results to understand their significance in view of staying lean in the first place . Normally, you would mean it does not depend if one fat cell holds a certain amount of fat or if this fat is held by two different cells. Unfortunately, it is a) much easier to "empty" one big fat cell which is about to burst anyway than two smaller cells and b) even if you emptied them completely that would leave you with more fat ...

Vitamin D Levels Associated with Adipose Fat Mass

Today is the day for our weekly news on vitamin D (never hard to find some ;-) Sciencists from Atlanta ( Lin. 2010 ) recently found that the dramatic weight loss patients experience after roux-en-y gastric bypass (RYGB) surgery goes hand in hand with an initial increase in plasma 25(OH)D concentration: Strong positive baseline and 1 month cross-sectional correlations between FAT and plasma 25(OH)D were observed, which remained after adjustment for age and race subgroup ( β = 0.76 and 0.61, respectively, P = 0.02) Interestingly, this intermittent increase was followed by a decreasing trend over the rest of the 24 month study period, so that Despite temporary improvement in vitamin D status, a high prevalence of vitamin D insufficiency was observed (76, 71, 67, and 82%, at baseline, 1, 6, and 24 months, respectively), and plasma 25(OH)D concentrations were lower in AA compared to white patients ( P < 0.05). The scientists conclude that in the course of the dramatic weigh...

Coumarins from the Stem Barks of Fraxinus rhynchophylla Inhibit Adipocyte Differentiation. A Novel Candidate for Weight Loss Supplement?

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A recent study by Shin et al. ( Shin. 2010 ) identified another potential weight loss drug: The Coumarins from the stem barks of Fraxinus rhynchophylla inhibited adipocyte differentiation and thus the basic mechanism of irreversible fat gain. Figure 1: Effects of Coumarins from F. rhynchophylla on Adipocyte Differentiation in 3T3-L1 Cells on days 1-6 ( Shin. 2010 ) As figure 1 shows, Esculetin a Coumarin from Fraxinus rhynchophylla is highly effective in inhibiting early adipocyte differentiation (day 1). With regard to the underlying mechanism of action, the scientists speculate: Esculetin (1) significantly blocked induction of PPARg expression in differentiated adipocytes, as measured by Western blot analysis (Fig. 4). In addition, esculetin (1) significantly inhibited adipocyte differentiation induced by troglitazone, a PPARg agonist (Fig. 5). These results suggest that esculetin (1) inhibited adipogenic differentiation, in part, via inhibition of PPARg -dependent pathway ....
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