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Orally Administered ATP (400mg) Increases Muscle Mass, Size and Performance Gains in Complex 12-Week Study With Previously Strength-Trained Subjects

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Training till you drop? Well with some ATP 30 minutes before your workout it may take a couple of minutes / workout sessions more to "drop" ;-) If you drive a Porsche that runs on super you would not put crude oil in the tank, would you? Well, why do you eat carbohydrates and fats then, when ATP, i.e. adenosine triphosphate, is the "fundamental energy unit" in our bodies? Why don't we guzzle ATP all day to run with the speed of light and lift with the force of an elephant? When? Well before, during and after a workout - sounds right, hah? Ok, ok, we are not "meant" to do so, I know... but even if you managed to keep the "paleo logic" out of the equation for once, there would be another stumbling block. Oral ATP is - supposedly - not bioavailable, at least that's what many people think. "ATP supplements are not orally bioavailable." In fact, Arts et al. even used the words in the subheading of this paragraph as the title...
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Lack of Drive? Theacrine Will Get You Going - Every Day! Camellia Kucha Alkaloid Acts via Dopamine and Adenosine

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Image 1: Coffee vs. tea, if it comes to the persistent dopaminergic "get going" effect it appears that a hitherto hardly known tea variety, Camellia Kucha has the edge on the #1 average westerner's #1 morning drink. Caffeine is the #1 drug for anyone looking for that little extra of burst of energy and yet there are people who claim they would kill for their morning coffee, while others swear by having one cup right before bed to keep the blood sugar levels from dropping during the night. Whatever your personal preference may be, it probably did not escape your notice that cup no.10,000 does not exert the same magic as cup  no. 10, decades ago. The reason for that is a pretty rapid habituation effect, the extend of which varies remarkably from person to person.If you do belong to the vast majority of people for whom  the morning coffee has become more of an entrenched habit than an energizer, you will therefore probably be interested in the results of a recent study...
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Cirsimarin: An Almost Completely Overlooked Lipolytic Agent

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It is interesting that, with the exception of USP Labs , who happen to have a talent to find "unorthodox" ingredients for their products, no supplement company has yet sourced an extract from Microtea debilis . After all, a similar extract ("similar" to the one used in USP Lab's Recreate ) was found to exert strong lipolytic properties being 20 times more potent than caffeine in a 2005 study by Girotti et.al. (cf. Girotti, 2005 Fig.1, below) Although the mechanism of action has not yet been fully investigated, a previous study by Hasrat et.al. found an antagonistic interaction with adenosine receptors similar to that of caffeine ( Hasrat. 1997 ). The exact effect of Cirsimarin differs however from that of caffeine and the less pronounced effects Gingko biloba, so that the researchers conclude: "This suggests that [...] the lipolytic activity of cirsimarin is related to another mechanism. [...] Studies to identify the precise mechanism of action of cir...
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