Opposing Effects of Resveratrol Depend on Dosage
While the hype about resveratrol appears to be over, it is still one of the cornerstones of many people seeking to improve health or promote longevity. If you belong to this group of people, you might find it interesting that without proper dosing, resveratrol may in fact do the exact opposite of what you were paying for. A recent review published in Human and Experimental Toxicology ( Calabrese. 2010 ) summarizes the literature as follows: The current assessment indicates that low concentrations of resveratrol can be potentially beneficial or harmful , depending on the endpoint of interest. The data suggest that low doses of resveratrol would have the capacity to increase the risk of tumor development of a number of organs based on its capacity to enhance cell proliferation in multiple human tumor cell lines. In contrast, a strong case can be made that low doses of resveratrol can be significantly cardio-protective . It is likely that these general conditions could occur simul...