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Conjugated Linoleic Acids: What's the Difference Between cis-9,11 and trans-10,12 CLA and Should We Label Them as "Transfats"? Plus: What Makes CLA Potentially Harmful?

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If Hayden Panettiere drinks it dairy can't be bad - despite (or because?) CLA, right? Well, what if I told you that Mrs. Panettiere was advertising milk in the "Got Milk" campaign despite being lactose intolerant? As a SuppVersity veteran you will be familiar with the idea that trans-10, trans-12 conjugated linoleic acid is the "fat burning" CLA isomer, while 9 cis,11 trans linoleic acid appears to blunt some of the pro-inflammatory actions of its cousin and has been shown to have specific physiological effects on it's own (e.g. increased bone health, cf. Platt. 2009; anti-cancer, cf. Corl. 2003). As I already mentioned, this is probably nothing new for you, if you make sure to get your daily dose of SuppVersity wisdom everyday. What you may however not be aware of is the fact that researchers like Ye Wang and Spencer D. Proctor are - despite the never-ending hoopla around potential weight loss effects of CLA - still contemplating, whether CLA could ...
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Vitamin D3 a "Fat Synthesizer"!? Rodent Study Shows +33% Increased Fat Deposition in Vitamin D3 Supplemented Mice.

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Illustration 1: Experts will recognize from looking at these Oil Red O-stained longissimus dorsi slices of mice on a normal and a vitamin D3 supplemented diet that supplemental (! not vitamin D from the sun !) "vitamin D3 can be used a s a fat synthesizer and meat tenderizer in meat-producing animals". (img in illustraton from Choi. 2011 ) I have been railing against the current vitamin D hype for months now. In that, I have at no point in time implied that "backfilling" depleted vitamin D levels via supplementation could not be beneficial (or at least not harmful), nor have I at any time excluded that vitamin D3 supplementation (even if you are in the "normal" range) could have its merit (cf. vitamin D3 + HMB ). What I have done though, was to point at the lack of controlled studies that would support any of the benefits supplemental vitamin D3 is currently hailed for all over the Internet. This amazes me, because the very same "gurus" who...
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