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SuppVersity Cellulite Special: The Etiology of Cellulite, Genetical and Behavioural Risk Factors? Physical and Supplemental Treatment Strategies & Their Efficacy

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This photo of a 37-year old woman some of you may already have seen Facebook testifies to the success of 12 weeks on 333U/cc retinol cream + high intensity laser pulses (Fink. 2006) I guess, or should I say, I'd hope (?) that some of you have already been waiting eagerly for the write-up of yesterday's Special Installment of the SuppVersity Science Round-Up on the Super Human Network and all the details and obviously the supps, Carl and I could not squeeze into this 1h+ show. Before you go over this huge (and this is also why it took me so long to post this) serving of the "Seconds", I do yet highly recommend that you download and listen to the podcast, first . You can grap the MP3, right here .  It's free and if you don't like the ads, just skip forward, but please come to terms with the fact that a daily 2h radio has to be financed one way or another! Let's dig right into this lumpy-bumby skin condition, now! Despite the fact that they did...

Gingko Biloba, Your Dopaminergic Brain Viagra. Plant Extract Stimulates Sexual Arousal via the Paraventricular Nucleus and the Mesolimbic System.

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Image 1: Gingko biloba trees are one of a kind, with no close living relatives (image Schwabe Pharm .) I bet you got one of those Viagra spam mails, today, as well, didn't you? Well, although I assume you would not need the small blue pills, anyway, you may be interest to read that researchers from the People's Republic of China may have found a viable Viagra alternative in a longstanding (pun intended ;-) ingredient of Traditional Chinese (and meanwhile also Western) Medicine : Gingko biloba . In order to elucidate the underlying mechanisms of previously ( Yeh. 2010 ) observed beneficial effects of Ginkgo biloba extract on noncontact erections in male rats, Yeh et al. ( Yeh. 2011 ) recorded both copulation, as well as non-contact erections in a group of 20 male Long-Evans (telling name, isn't it?) rats, which had been randomly assigned to a treatment ( 50mg/kg body weight Gingko biloba extract [EGb 761 from Schwabe Pharmac...

Ginkgo, Ginseng, Green Tea: Only one of the G's may be worth Supplementing

In the most recent episode of their supplement review (which is usually very critical) the British Journal of Sports Medicine ( BJSM Review. Part 17 ) has a look at studies on the ergogenic potential of ginkgo , ginseng and green tea , all of which are heavily advertised for their beneficial effects on health, long jeopardy and mental, as well as physical performance. In the case of Ginkgo an Ginseng, the studies that have been considered in this review provide very inconclusive evidence for and against their use as ergogenics or medical plants. With regards to the underlying reasons for the discrepancies which have been reported, the reviewers argument that both, the origin, as well as the processing techniques may have influenced the efficiency of ginkgo and ginseng products. green tea , on the other hand, "shows some promise" - regular readers of this review series will know that this is already a great praise! Although evidence is limited, green tea extract, ...

Cirsimarin: An Almost Completely Overlooked Lipolytic Agent

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It is interesting that, with the exception of USP Labs , who happen to have a talent to find "unorthodox" ingredients for their products, no supplement company has yet sourced an extract from Microtea debilis . After all, a similar extract ("similar" to the one used in USP Lab's Recreate ) was found to exert strong lipolytic properties being 20 times more potent than caffeine in a 2005 study by Girotti et.al. (cf. Girotti, 2005 Fig.1, below) Although the mechanism of action has not yet been fully investigated, a previous study by Hasrat et.al. found an antagonistic interaction with adenosine receptors similar to that of caffeine ( Hasrat. 1997 ). The exact effect of Cirsimarin differs however from that of caffeine and the less pronounced effects Gingko biloba, so that the researchers conclude: "This suggests that [...] the lipolytic activity of cirsimarin is related to another mechanism. [...] Studies to identify the precise mechanism of action of cir...
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