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Fat Burning Grains? Japanese Study Says: The Peppery "Grains of Paradise" Actually Qualify as True Thermogenics

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If you are as cool as the subject on the right (no black dots in the neck and trap area = no BAT activity) you don't have to keep thinking about BAT thermogenesis (img from Sugita.2013) "Grains are the root of all our problems." It would be nice if it really were that simple... what would be even better is if they turned out to be the solution, as well. Wouldn't that be paradise? It would. And what's more, it could! At least if the Grains of Paradise , i.e. the seeds of Aframomum melegueta(Rosco) K. Schum.) (GP) , Guinea pepper or Alligator pepper would increase thermogenesis a significant amount more than those ~6kcal/h that have been observed in healthy non-obese subjects in a recent study by Jun Sugita and his (or her?) colleagues from the Department of Nutrition at the School of Nursing and Nutrition of the Tenshi Collage in Japan (Sugita. 2013). . ~6 kcal/h in BAT positive subjects that's definitely not enough The mechanism by which the ingestio...

Fat Burners Don't Work in the Obese!? BAT Activity Almost Zero, Even after the Ingestion of ~290mg Ephedrine!

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Do thermogenic fat burners only work if you already look like this? I mean, what would be the sure, then and why did the ECA stack work for overweight people, as well? I don't know if you have ever thought about the problems mostly involuntarily obese individuals are facing in their everyday lives!? Even if you discard the constant bullying and the subliminal messages they receive from their peers, not fitting into a regular seat in an airplane certainly is more than just an embarrassment. Now what would you say, if I told you that they are discriminated against even, when they shop at their local GNC, or whichever other supplement vendor they may be using? And I am not talking about the lean guys and girls on the labels of the supplements, here! No, I am referring to a discrimination that takes place on a more fundamental level and it happens right in front of the shelf with every overweight person's favorite supplements: The so-called fat burners! Ok, now that I got eve...

Ephedrine, Exercise or Diet? Ephedra Modulates Substrate Utilization, but Exercise Melts Body Fat & Builds Muscle

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Image 1: Twinlabs' made a fortune on their line of ephedra containing fat burners. For many people ephedrine, the "E" in the infamous ECA stacks and the alkaloid from the mua huang on which Twinlab and co. made a fortune in the late 1990s, was the first and only truly working fat-burner on the supplement market. "Legendary", "unique", "unparalleled", these are the attributes by which they like to refer to their old-school fat burner. What's missing from most of these stories, though, are the hardships, the hours of intense training and weeks of radical dieting that may have become more bearable, yet by no means obsolete with the use of respective products. A 2012 look at diet, exercise and ephedrine In a soon to be published paper, Nikki Sclotum and her colleagues from GlaxoSmithKline , the North Caroline State University and the Purdue University report on the results of an experimental comparison of ephedrine, diet and ex...

BAT: Brown Adipose Tissue in Humans - An Update

In the latest edition of Current Opinion in Lipidology we find a mini-summary ( COL. 2010 ) on current findings on the existence and metabolic purpose of brown adipose tissue (BAT) in human beings. These days the previously accepted position that adults have little to no BAT is put into question by the results of PET, where brown fat becomes especially visible upon cold exposure, when its metabolic activity is increased as a result of thermogenesis. The author points out that adipocytes (fat cells) and myocytes (muscle cells) do not only share the same origin, the metabolically active BAT exhibits other similarities to muscle cells, as well - it is a metabollically active tissue and of particular importance in the context of insulin sensitivity and glucose disposal: BAT glucose uptake rate is 10-15-fold higher in cold than in normal room temperature. Other factors that may increase the activity of sympathetic nervous system and uncoupling protein 1 are several including the comp...
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