Phosphatidic Acid Supplementation Fails to Augment the Benefits of Resistance Training in Trained Young Men
Phosphatidic Acid Powder, Pills or Whatnot - Yet Another Supp You Do Not Need? Or “Possibly” and “Likely” Good for Individuals with a Minimum of 1 Year Gym Experience (3+ workouts/wk) ? The observation that phosphatidic acid (PA) will promote the expression of the mTORC1 and thus trigger an increase in protein synthesis has created some excitement among supplement junkies. After all, it would seem as if PA could thus be yet another agent on the short list of effective muscle builders ... the problem with the existing research, however, is that it is contradictory. Of the three hitherto published studies by Hoffman et al. (2012); Joy et al. (2014), and Escalante et al. (2016), only one study, i.e. the one by Escalante et al. appears to confirm that PA supplementation will augment the beneficial effects of controlled resistance training in the absence of potentially confounding factors such as the provision of additional supplements in form of leucine, HMB and vitamin D in the st...
