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Tune Your Brain With Creatinyl Amino Acids: "Neuro-Ergogenic" New Wonder-Creatines Readily Pass the Blood Blain Barrier and Are Potential Candidates for Treatment and Prevention of Stroke.

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Image 1: Photograph of acute MCA stroke. Image taken at autopsy on 10-24-2006 [MODIFIED BACKGROUND]; photographer Marvin 101 @ Wikipedia.org Alpha-methylguanidino acetic acid, is an amino acid, everyone of you will be familiar with: creatine. And though this may not be the first time you will have heard of its beneficial effect on brain health, the synthesis of new forms of creatine, so called creatinyl amino acids by guanidinylation of sarcosyl peptides or creatine p-toluenesulfonate [both reactive processes in the course of which the new creatinyl amino acid is formed] appears to offer exciting new possibilities for creatine derivates in the prevention and treatment of stroke and other neurological pathologies. In a paper, recently published in the official Journal of the European Peptide Society, Peptide Science , Burov et al. ( Burov. 2011 ) describe the synthesis and possible use of advanced hydrophobic creatine hybrids...
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Scientific Evidence Links High Carbohydrate Intake to the Development of Alzheimer's and Other Neurological Diseases

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"Fats are bad, carbs are healthy!" I hope nobody out there still believes this late 20th Century slogan. If you do, chances are you will soon forget about it due to the neuronal damage you are inflicting to your brain by eating a high carb diet. In a very recent review, a group of international scientists ( Seneff. 2011 ) summarize the current state of research as follows: [...] an excess of dietary carbohydrates, particularly fructose, alongside a relative deficiency in dietary fats and cholesterol, may lead to the development of Alzheimer's disease. A first step in the pathophysiology of the disease is represented by advanced glycation end-products in crucial plasma proteins concerned with fat, cholesterol, and oxygen transport. This leads to cholesterol deficiency in neurons, which significantly impairs their ability to function. Over time, a cascade response leads to impaired glutamate signaling, increased oxidative damage, mitochondrial and lysosomal dysfu...
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Nootropics: Phosphatidylserine for Smarter Athletes

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While Phosphatidylserine is marketed mainly for its purportedly beneficial effect on exercise recovery and cortisol levels, a recent study by Parker et al. ( Parker .2010 ) showed that supplementation with 400 mg/day Phosphatidylserine (SerinAid, Chemi Nutra) for 14 days before testing, significantly reduced the time needed for a correct calculation by 19.8% (1.27 s per calculation; Placebo: 6.4 s, PS 5.13 s; p = 0.001), and reduced the total amount of errors by 33% (PRE: Placebo: 27, PS: 18, p = 0.18) at PRE compared to placebo. Exercise significantly improved SST time (p = 0.03). PS did not improve SST compared to placebo post exercise. So, wheter you have your math test before or after your workout, do not forget to get your daily dose of phosphatidylserine in ;o)
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