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Cinnamon as Nutrient Partitioner and 1st-Line Treatment for Pre-Diabetes? 5% Decrease in Fasting Glucose per Month in Human Studies, Up to 24% in 40 Days W/ High(er) Doses

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Yes, that's how real cinnamon look like. It does not grow as powder in plastic boxes on trees as I suspect the members of the generation McBurgerSubway believe ;-) No, this is not  absolutely new. In fact this is just "another" SuppVersity  articles on the anti-diabetic effects of cinnamon, but I promise it's going to be the most comprehensive one. One that discusses the currently available evidence from human trials, as well as the things we know and believe to know about how cinnamon acts its anti-diabetic magic qualitatively and quantitatively. Before I even go into further details, though, I would like to address one of the "cinnamon myths" that says that only the highly expensive Ceylon or Sri Lankan Cinnamon would do the trick, while the commonly sold Cinamon cassia would be useless or even dangerous due to its high (and in fact toxic) coumarin content. Trying to improve your blood glucose management? Learn how at the SuppVersity Protei...

Science Round-Up Seconds: Does the Paleo Diet Ruin Your Lipid Profile? Plus: Liver Health & Hepatitis - Milk Thistle & Beyond. Libido Boosters & Real PDE-5 Inhibitors. "Fake" Cinnamon, Coumarin, Bloodthinning & Carcinogenic Cereals.

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Is the Paleo Diet unhealthy for healthy individuals? A recent thesis would suggest just that. Learn more about and make up your mind based on the last installment of the Science Round-Up and today's Seconds (img informedhealth.com.au) I hope you did not miss that the SuppVersity Science Round-Up will as of now always be starting early(-ier) at 12PM EST. If so, don't worry, you can still download the show and listen to Carl and me talking about the things you may be missing, the ones you get extra and those you would rather not have in your supplements and foods. Let's take silymarin , for example, as you have learned on the show, not all "liver assist", "liver clense" or "liver health" products are created equal. Most intriguingly, their ability to scavenge free radicals, as measured by the trolox assay, is not singularly dependent on the actual silymarin content, but will - as the data from the study Anthony et al. conducted (Anthony....

Coumarins from the Stem Barks of Fraxinus rhynchophylla Inhibit Adipocyte Differentiation. A Novel Candidate for Weight Loss Supplement?

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A recent study by Shin et al. ( Shin. 2010 ) identified another potential weight loss drug: The Coumarins from the stem barks of Fraxinus rhynchophylla inhibited adipocyte differentiation and thus the basic mechanism of irreversible fat gain. Figure 1: Effects of Coumarins from F. rhynchophylla on Adipocyte Differentiation in 3T3-L1 Cells on days 1-6 ( Shin. 2010 ) As figure 1 shows, Esculetin a Coumarin from Fraxinus rhynchophylla is highly effective in inhibiting early adipocyte differentiation (day 1). With regard to the underlying mechanism of action, the scientists speculate: Esculetin (1) significantly blocked induction of PPARg expression in differentiated adipocytes, as measured by Western blot analysis (Fig. 4). In addition, esculetin (1) significantly inhibited adipocyte differentiation induced by troglitazone, a PPARg agonist (Fig. 5). These results suggest that esculetin (1) inhibited adipogenic differentiation, in part, via inhibition of PPARg -dependent pathway ....
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